10 Best lubricating eye drops (2025)

10 Best lubricating eye drops (2025) offer effective relief for dry, irritated eyes, ensuring comfort and clarity. These top-rated products are formulated with advanced ingredients to mimic natural tears, providing long-lasting hydration. Popular choices include brands like Systane, Refresh, and Blink, each offering unique benefits such as preservative-free options and enhanced moisture retention. Users appreciate the soothing effects and quick absorption of these drops, making them ideal for daily use or occasional relief. With a variety of formulations available, finding the perfect lubricating eye drops to suit individual needs has never been easier.

SaleBestseller No. 1
Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)
  • IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
  • MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
  • CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
  • GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
  • PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.
Bestseller No. 2
Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
  • #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
  • Extended Protection
  • Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
  • Reduces both the signs and symptoms of dry eye
  • Quickly soothe irritated eyes wherever you are
SaleBestseller No. 3
TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, 0.5 fl oz Bottle, 2 Count(Pack of 1)
  • Get up to 12 Hours of Hydrating Comfort; TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops provide EXTRAordinary relief for dry eyes
  • Discover TheraTears eye drop; one-of-a-kind silky hydration for dry eyes
  • Lubricating eye drops for extra dry eyes rehydrate; protect against further irritation and support a natural tear pH level
  • TheraTears Extra Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
  • TheraTears corrects the salt imbalance that can cause dry eye symptoms
SaleBestseller No. 4
TheraTears Dry Eye Therapy Eye Drops for Dry Eyes, 0.5 Fl Oz
  • TheraTears Dry Eye Therapy - Lubricant Eye Drops provide immediate, long lasting relief of dry eye symptoms
  • Restores Eyes Natural Balance
  • Unique hypotonic and electrolyte balanced formula replicates healthy tears
  • Preservative free in the eye
  • Convenient, multi-use bottle
Bestseller No. 5
Visine Dry Eye Relief Lubricant Eye Drops with Polyethylene Glycol 400 to Moisturize and Soothe Irritated, Gritty and Dry Eyes, Designed to Work Like Real Tears, 0.5 fl. oz
  • 0.5-fluid ounce bottle of Visine Dry Eye Relief Lubricant Dry Eye Drops to provide dry eye relief and protection from further eye irritation
  • These sterile moisturizing eye drops provide soothing relief of dry, gritty and irritated eyes and are designed to work like real tears
  • The hydrating drops lubricate eyes, feature polyethylene glycol 400 and contain 10 ingredients found in your own natural tears
  • Helps relieve dry eye symptoms such as burning and irritation due to activities such as extended screen use while also helping to protect against further eye irritation.
  • Visine Dry Eye Relief Lubricant Eye Drops are available in a small, convenient-to-carry bottle for convenient relief anywhere, even on-the-go
SaleBestseller No. 6
Refresh Plus Lubricant Eye Drops, Preservative Free, Single Use Containers, 30 Count
  • Original strength, preservative-free formula
  • Relieves mild symptoms of eye dryness
  • Instantly moisturizes and lubricates
  • Designed to act like your own natural tears
  • Great for sensitive eyes
SaleBestseller No. 7
TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials
  • TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
  • Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
  • TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
  • TheraTears corrects the salt imbalance that can cause dry eye symptoms
  • Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness
SaleBestseller No. 8
Blink Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz
  • Relief with every Blink: Experience extended dry eye symptom relief with Blink Triple Care Lubricating Eye Drops. This 3-in-1 formula instantly soothes, gives extra long-lasting hydration, and seals in moisture.
  • Dry Eye Lubricant: Discover what makes Blink Triple Care Lubricating Eye Drops different from other eye drops. Our drops for dry eyes have a dual-action moisture seal to lock in moisture for instant, long-lasting relief.
  • Long-Lasting Hydration: Blink Triple Care Lubricating Eye Drops are formulated with hyaluronate - also found in your eyes - to boost hydration. Hydrate like your tears for extra long-lasting comfort
  • Reduce Everyday Discomfort: These dops for dry eyes deliver extended relief for moderate to severe dry eye symptoms
  • Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated.
SaleBestseller No. 9
Refresh Liquigel Lubricant Eye Gel Drops, 0.5 Fl Oz Sterile
  • Original strength gel formula
  • Relieves dry, burning, irritated eyes
  • Alleviates discomfort
  • Keeps eyes feeling better longer
  • Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey
SaleBestseller No. 10
Blink GelTears Eye Drops for Dry Eyes, Gel Lubricating Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz
  • Relief with Every Blink: Experience immediate and long-lasting dry eye symptom relief with Blink GelTears eye drops for dry eyes. This thicker, more viscous lubricating formula is for enhanced comfort and great for daytime and nighttime use
  • Hydration Boost with Hyaluronate: Our gel lubricating eye drops for dry eyes instantly soothe and comfort. It contains our highest level of hyaluronate to provide longer lasting relief for moderate to severe dry eye symptoms
  • Day & Night Relief: Blink eye drops are formulated for daytime and nighttime use and provides superior end-of-day comfort (in an Ocular Lubricant questionnaire, comfort ratings were statistically significantly higher for Blink GelTears vs. Allergan’s Refresh Optive Liquid Gel after 7 days and 30 days).
  • Reduce Everyday Discomfort: These drops are an extra moisturizing gel for enhanced comfort. Work with every blink to restore your tears' natural balance and maximize hydration
  • Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated.
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