10 Best expectorants (2025) offer effective relief for those struggling with mucus and congestion. These products, ranging from natural remedies to over-the-counter medications, help thin and loosen mucus, making it easier to expel. Popular choices include guaifenesin-based formulations, herbal options like thyme and eucalyptus, and combination products that target multiple symptoms. Users appreciate their fast-acting properties and minimal side effects, making them suitable for various age groups. As always, it's essential to consult with a healthcare professional before starting any new treatment to ensure safety and effectiveness tailored to individual needs.
SaleBestseller No. 1
GenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies
- FAST RELIEF - GenCare mucus relief Guaifenesin is an expectorant that helps loosen and thin mucus in your throat so you can breathe easier through your nose and mouth while expelling mucus and phlegm.
- FIGHTS COLDS - Combat chest congestion, mucus and bronchial secretions caused by the common cold and flu. This product is not for children under 12 years of age.
- EASY SWALLOW TABLETS - Avoid foul tasting cough syrups and liquids that need to be taken every couple of hours for lasting effects. Easy to swallow to provide fast and sustained mucus relief during the day and night.
- BULK SAVINGS - You and your family will always have cough and congestion relief on hand. Save money with the same active ingredient as Mucinex and Robitussin Mucus + Chest Congestion at a fraction of the price.
- 100% SATISFACTION GUARANTEE - Our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers and families...Click Add-to-Cart to order Today!
Bestseller No. 2
Amazon Basic Care Guaifenesin Cough and Mucus Relief Extended-Release Tablets, 600 mg, 12 Hour Expectorant, 20 Count
- ACTIVE INGREDIENT: Amazon Basic Care Cough and Mucus Relief contains Guaifenesin 600 mg, an expectorant; compare to the active ingredient in Mucinex
- 12-HOUR RELIEF: Get immediate and long-lasting chest congestion relief; just one dose releases the regular strength phlegm relief medicine you need and lasts for up to 12 hours
- COUGH EXPECTORANT: Trust Guaifenesin 600 mg to thin and loosen mucus to make coughs more productive
- MUCUS RELIEF: Amazon Basic Care Cough and Mucus Relief Extended-Release Tablets relieve chest congestion caused by excess phlegm
- GLUTEN FREE: This product is free of gluten; safe for adults and children 12 years of age and older
SaleBestseller No. 3
Mucinex 12 Hour 1200mg Maximum Strength Guaifenesin Chest Congestion & Mucus Relief, Guaifenesin Expectorant Aids Mucus Removal, Chest Decongestant for Adults, Dr Recommended, 42ct Tablets
- EXCESS MUCUS RELIEF: Maximum Strength Mucinex 12hr extended-release tablets pack a powerful punch with 1200 mg guaifenesin expectorant, providing you with long-lasting chest congestion relief
- AIDS EXCESS MUCUS REMOVAL: Maximum strength chest congestion relief; Mucinex 12hr lasts up to 12 hours and provides relief for your chest congestion and makes cough more productive
- EXPECTORANTS FOR ADULTS: Mucinex helps clear lungs by thinning & loosening mucus; Say goodbye to excess mucus, say hello to chest congestion relief
- EXTENDED RELEASE GUAIFENESIN: Experience long-lasting excess mucus relief with Mucinex's 12hr maximum strength extended-release 1200 mg guaifenesin bi-layer tablets with immediate & extended release
- TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend
Bestseller No. 4
Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant, 14 Tablets
- ACTIVE INGREDIENTS: Amazon Basic Care Maximum Strength Mucus Relief DM tablets contain dextromethorphan HBr and guaifenesin; compare to the active ingredients in Maximum Strength Mucinex DM
- MAXIMUM STRENGTH: 1200 mg of guaifenesin and 60 mg of dextromethorphan HBr team up to take on your toughest cold
- EFFECTIVE: Amazon Basic Care Maximum Strength Mucus-DM clears your chest congestion and eases the intensity of coughing
- COUGH SUPPRESSANT: This 12-hour cough medicine contains dextromethorphan HBr for cough relief; it relieves the impulse to cough to help you get to sleep
- COUGH EXPECTORANT: Contains guaifenesin to help loosen phlegm so you can cough up that bothersome mucus; makes coughs more productive
Bestseller No. 5
Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor - 8 Fl Oz Bottle
- One 8 fluid ounce bottle of Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor
- Non drowsy cough medicine that controls and relieves frequent cough, plus thins mucus to relieve chest congestion
- Liquid cough expectorant that's easy to measure and administer
- Raspberry flavored cough and chest congestion expectorant provides fast relief
- Non drowsy cough suppressant relieves symptoms without slowing you down
Bestseller No. 6
Mucinex 12 Hour 600 mg Guaifenesin Extended-Release Tablets for Excess Mucus Relief, Expectorant Aids Excess Mucus Removal, Chest Congestion Relief, 20 Bi-Layer Tablets
- EXCESS MUCUS RELIEF: Mucinex 12hr extended-release tablets pack a powerful punch with 600 mg guaifenesin expectorant, providing you with long-lasting chest congestion relief
- AIDS EXCESS MUCUS REMOVAL: Mucinex SE lasts up to 12 hours, provides chest congestion relief and makes coughs more productive
- EXPECTORANTS FOR ADULTS: Mucinex helps clear lungs by thinning & loosening mucus; Say goodbye to excess mucus, say hello to chest congestion relief
- EXTENDED RELEASE GUAIFENESIN: Experience long-lasting excess mucus relief with Mucinex's 12hr extended-release 600mg guaifenesin tablets; our original bi-layer tablets have both immediate & extended release
- TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend
Bestseller No. 7
HEALTH LFE Mucus Relief Guaifenesin Caplets 400 mg, Immediate Release Fast Acting Expectorant, Thin and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (Medium, 200 Count)
- ✅ ACTIVE INGREDIENT: The active ingredient in this product is Guaifenesin, an expectorant that helps reduce chest congestion caused by colds, infections or irritants. Clinically proven to provide powerful relief for your toughest chest congestion.
- ✅ FAST ACTING: HealthLife Guaifenesin is a fast-acting expectorant helps loosen and thin mucus. Take 1 tablet every 4 hours with water.
- ✅ EASY TO SWALLOW: Our 400 mg tablets are small in size making it easier to swallow to promote clearer breathing by providing continuous relief through out the day and night. Enjoy cough mucus relief with tablets that can be used by those with allergies, colds, infections, and flu bugs.
- ✅ VALUE PACK SAVINGS: Did you know, with HealthLife Guaifenesin of 60 count value pack can save you significant amount of money with the same active ingredient Leading Brands..
- ✅ MADE IN USA: A Non-Drowsy Immediate Release Formula carefully manufactured in USA to gurantee 100% satisfaction.
Bestseller No. 8
Guardian Mucus Relief 12 Hour (70 Count) Extended Release Guaifenesin, 1200mg Maximum Strength, Chest Congestion Expectorant Tablets (70 Count Bottle (Pack of 1))
- Whether it's the spring or fall allergy season Guardian Mucus Relief has you covered. Guardian Mucus Relief MAXIMUM STRENGTH Relieves Chest Congestion
- Thins and loosens Mucus, Makes Coughs more productive
- Convenient Packaging- Tired of fumbling with blister packs? - Get 70 tablets in a bottle - For chronic users the bottle pack is more convenient - no mess and no fuss of removing each pill from the blister pack
- Extended Release. Gets to work right away and each pill lasts 12 hours. BLUE DYE FREE
- 1200mg 70 Count BOTTLE. EXTENDED RELEASE Maximum Strength -Made in USA
Bestseller No. 9
Robitussin Adult Maximum Strength Cough + Chest Congestion DM Max (8 fl. oz. Bottle), Cough Suppressant & Expectorant, Raspberry Flavor
- One 8 fl oz bottle of Robitussin Maximum Strength Cough and Chest Congestion DM Liquid, Congestion Relief and Cough Medicine, Berry Flavor
- Cough suppressant for relief for cough and an expectorant for relief of chest congestion
- Maximum-strength formula with expectorant that thins and loosens mucus for productive coughs
- Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
- Suitable for adults and children 12 years and over