10 Best mushroom supplements in 2025 offer a range of health benefits, harnessing the power of various fungi to enhance wellness. These supplements, including popular options like reishi, lion's mane, and cordyceps, are celebrated for their potential to boost immunity, improve cognitive function, and increase energy levels. With advancements in extraction methods, the quality and potency of these products have significantly improved. Brands like Four Sigmatic, Host Defense, and Om Mushroom Superfood lead the market, providing consumers with effective and convenient ways to incorporate the benefits of mushrooms into their daily routines.
Bestseller No. 1
FreshCap Ultimate Mushroom Complex - Ayurveda Lions Mane, Reishi, Cordyceps, Chaga, Turkey Tail, Maitake - Immune Support & Nootropic Supplements for Immunity, Energy, Memory & Focus (120 Capsules)
- Ultimate Immune Support Supplement: FreshCap's Ultimate Mushroom Complex delivers all the amazing benefits of mushrooms including enhanced immunity, focus, and energy. Each capsule contains 1,000mg of the extract, which is equivalent to 12,000mg of raw mushrooms, due to the 12:1 extraction ratio. This powerful formula combines 6 of the most researched mushroom species (Lion's Mane, Reishi, Cordyceps, Chaga, Turkey Tail & Maitake).
- Organic, Powerful & Active Compound Verified: Our mushroom supplements are CCOF Certified Organic, Non-GMO, Gluten Free, Vegan and Paleo friendly. All supplements are 3rd party tested and scientifically verified to contain greater than 29% beta-glucans, which are the beneficial compounds you’re looking for, and to guarantee purity and quality.
- No Fillers, Stop the Grain: We use only whole mushroom fruiting bodies with no filler, mycelium, extra starch or grains. Many of our competitors use mycelium-based products that are grown on grain, which means you are buying product that has filler like brown rice or oats (even if they claim otherwise). It is nearly impossible to separate mycelium from the grain base. Make sure to look for whole fruiting body based products.
- Easy To Use: Each bottle contains 120 capsules and is a 2 month supply at the recommended serving size (2 capsules/day). Our capsules are easy to use, and can be taken with you anywhere you go. Mushroom supplements are a great addition to all of your existing supplements (e.g. multi-vitamins) and FreshCap's mushroom powder can be a great addition to make mushroom coffee or enhance your smoothies, shakes and tea.
- Trust the Experts: We want you to feel amazing and be happy. Get what you’d expect from a premium mushroom supplement.
SaleBestseller No. 2
10 in 1 High Strength Mushroom Supplement 9,700MG - Lions Mane, Cordyceps, Reishi - Brain Supplements for Memory and Focus ** 5-Month Supply
- HIGHEST POTENCY: With just 1 convenient capsule, you'll get all the potent of 10 top tier mushrooms highly concentrated into this 10 in 1 formula. Say goodbye to juggling multiple mushroom supplements - Vegatot Mushroom Complex is all you need to perform at your best.
- MOST POWERFUL COMBINATION: Our formula contains an incredible 10 mushroom species, each chosen for their unique nutritional profile and health benefits. With Lions Mane, Cordyceps Sinensis, Reishi, Turkey Tail, Maitake, Chaga, Shiitake, Enoki, Agaricus, and Oyster mushrooms. These mushrooms together provide a comprehensive range of potential benefits for your body and mind, including immune system support, improved focus and other brain functions.
- ULTIMATE MUSHROOM EXTRACTION: Not only do these mushrooms provide such health benefits, but we also use the most potent form of their extraction to ensure maximum potency and effectiveness. Being extracted from 𝟵𝟳𝟬𝟬𝗠𝗚 dry powder, each serving of our complex is made using a special process that concentrates the bioactive compounds found in mushrooms, resulting in a more potent and effective than other supplements on the market.
- PURE INGREDIENTS, PURE PEACE OF MIND: Vegatot is committed to providing pure, high-quality supplements that give you peace of mind. Our ingredients are tested strictly by third-party ISO 17025-accredited labs to ensure purity and safety. They are vegan-friendly and free from artificial colors, flavors, preservatives, and common allergens such as gluten, wheat, dairy, soy, sugar, and yeast. Therefore, you can feel good about what you're putting into your body
- PREMIUM VALUE AT A FAIR PRICE: At Vegatot, we manufacture our products in a cGMP-certified facility, ensuring the highest standards of quality. And to make it even better, we offer these premium products at an affordable price, so you can reach your full potential without any extra financial stress.
Bestseller No. 3
Clean Nutraceuticals Lions Mane 20in1 Mushroom Supplement with Turkey Tail Reishi Cordyceps Chaga Maitake Meshima Poria Cocos Shiitake Oyster Porcini Enoki - Pack
- Advanced Mushroom Complex For Women And Men - Our mushrooms supplement includes 20 different types of mushroom extract such as lions mane mushroom capsules, turkey tail mushroom extract, reishi mushroom powder, chaga mushrooms capsules, and cordyceps sinensis. A potent Lions Mane Mushroom Supplement with lions mane extract has been created and the results are amazing. Clean Nutra has made an all-in-one lions mane supplement with turkey tail mushroom capsules, chaga mushrooms powder and more.
- The Ultimate Mushroom Supplement Capsules You’ve Been Looking For - Clean Nutraceuticals ShroomZoom provides 5 full-dose mushroom supplements in one, containing a full lions mane powder, turkey tail mushroom powder, reishi mushroom extract, chaga powder, and cordyceps capsules in a convenient 2 capsule dosage! Finally, lions mane capsules, turkey tail mushrooms, reishi powder, and cordyceps mushroom powder have been packed into one convenient solution that's easy to take.
- Introducing the ShroomZoom Blend - In addition to lions mane mushroom powder, turkey tail extract, reishi mushrooms, chaga mushroom powder, and cordyceps extract our formula also contains 15 additional powerhouse mushrooms such as Maitake, Meshima, Poria Cocos, Shiitake, Tremella, Oyster, Agaricus, Porcini, Enoki and more! These mushroom complex capsules are a powerful alternative to lions mane tea, reishi mushroom tea, reishi coffee, chaga coffee, lions mane tincture and lions mane gummies.
- A Powerful All In One Support Supplement - ShroomZoom is overflowing with potent lions maine, turkey tail capsules, reishi mushroom capsules, chaga extract, and cordyceps sinensis powder. Clear out those countless supplements in your supplement cabinet like reishi mushroom gummies and take just one lions main, turkey tail mushroom supplement, reishi extract, chaga pills and cordyceps supplement containing an overall 20-in-1 mushroom pills formula from Clean Nutraceuticals.
- Vetted and Trusted Ingredients - We pride ourselves in offering quality supplements for our customers. Our mushroom formulas are proudly made in a registered and certified facility to create trusted lions mane, turkey tail mushroom supplements, reishi mushroom supplement, and cordyceps powder complexes for men and women. Other alternatives consist of organic lions mane, lions mane powder organic, cordyceps militaris and red reishi mushroom powder.
SaleBestseller No. 4
Nutricost Mushroom Complex Supplement, 120 Capsules - 10 Mushroom Blend (with Reishi, Maitake, Shiitake, Lion's Mane, and More) - Non-GMO and Gluten Free
- 5,500mg Equivalent Mushroom Complex
- 10 Mushroom Blend (With Reishi, Shiitake, Lion's Mane, And More)
- 120 Servings Per Bottle
- Non-GMO, Gluten Free, 3rd Party Tested
- Made in a GMP Compliant, FDA Registered Facility
SaleBestseller No. 5
Genius Mushroom Supplement - Lions Mane, Cordyceps, Reishi - Brain Nootropic for Energy, Focus, Overall Wellness, & Immune Support - 90 Capsules
- Nurture: Genius Mushrooms by The Genius Brand combines 3 of the most researched mycological species on the planet that help enhance clarity, system support function, and more. Genius Mushrooms are keto, paleo, and vegan friendly. Serving size - 3 capsules, 30 servings per container
- System Booster: Step up your support with Reishi Mushroom Extract. Used for centuries, this booster is what you need to help keep yourself in check and dodge common ailments
- Caffeine-Free Energy: Lion’s Mane provides boosting benefits to support focus, function, and mood. Cordyceps helps elevate your energy levels via ATP (natural energy) production, allowing for increased oxygen utilization and athletic endurance
- How to Use: Take 3 capsules with 8 oz of water 20 minutes before a meal once a day. You may also take 1 capsule three times daily before meals, if preferred
- Supplement Smarter: Genius Brand supplements are a rejection of backwards industry dogma that misled generations of enthusiasts. For us, innovation and science-backed ingredients come first. Whether you’re a pro athlete, stay-at-home parent, retiree, or anything in between, our products can be of benefit to you. We’re all humans, and we are in this together
Bestseller No. 6
Organic 10-in-1 Mushroom Supplement 8,000mg Per Serving, 240 Capsules – Lions Mane, Turkey Tail, Reishi, Cordyceps & More Mushroom Complex – Immune, Energy & Nootropic Brain Support – Non-GMO
- Special Features – Organic mushroom 10-in-1 active blend, fresh mushrooms grown and harvested in the US, ultimate adaptogenic complex, 8,000mg herbal equivalent serving.
- Benefits & Use – High concentrated proprietary and extract blend, offers synergistic benefits for immune, energy, and brain nootropic health in men and women.
- Dosage & Servings – 240 real mushroom capsules, 2 capsules per serving, provides a 15:1 extract 1,500mg serving of lions mane, chaga, reishi, turkey tail, and cordyceps with a 400mg 4:1 extract of shiitake and a 100mg proprietary blend that includes wood ear, oyster, maitake, and mesima.
- Purpose – These mushrooms have been trusted for centuries and combining them together creates the ultimate superfood complex, providing essential adaptogens, antioxidants, beta-glucans, vitamins, and minerals.
- Quality Ensured – Non-GMO ingredients that are 3rd party lab tested and passed. Made without gluten, dairy, eggs, peanuts, soy, wheat, yeast, and tree nuts.
Bestseller No. 7
NutriFlair Mushroom Supplement 2600mg, 90 Capsules - 10 Mushrooms Blend - Reishi, Lions Mane, Cordyceps, Chaga, Turkey Tail, Maitake, Shiitake, Oyster Nootropic Complex - Brain, Energy, Focus Pills
- 10 Powerful Mushroom Blend 2600 Mg - NutriFlair Mushroom Supplement features 10 types of mushroom - Cordyceps, Reishi, Lion's Mane, Chaga, Turkey Tail, Maitake, Shiitake, Enoki, Agaricus, and Oyster Mushrooms, all working together to promote outstanding daily health. Our maximum dosage mushroom complex of 2600mg per serving is the highest available potency on the market today.
- ✔ Supports Healthy Immunity ✔ Promotes Focus, Clarity, Memory, Heart Health - Are you tired of frequently falling ill or catching a cold? Our mushroom capsules can help strengthen your immune defenses and keep your body strong and alert. Experience increased energy levels and vitality as these mushroom capsules cleanse your system. Enjoy excellent cardiovascular function and enhanced focus and memory.
- Top Quality, Vegan, Non-GMO, Gluten free - Our professionally formulated mushroom pills, are made with pure, Vegan, Non-gmo, Gluten-free ingredients. Our capsules contain no Fillers, Soy, Preservatives, Binders, or chemicals. Often referred to as shroom, mushies, mushroom extract, giant mushroom, mini mushroom, white mushroom, moshroom, medicinal mushroom, amani, liberty cap. Mushroom is often combined with turmeric curcumin, other nootropics, cinnamon, lions mane supplement.
- Tested & Trusted Ingredients: NutriFlair soy-free, gluten-free and dairy-free, mushroom complex formula is manufactured in the USA, in a duly registered, approved, inspected state-of-the-art facility, with strict adherence to Good Manufacturing Practices (gmp). Each and Every batch is 3rd Party Tested for Quality, Purity, and Potency. This includes all our Best Quality capsules, tablets, pills, gummies, supplements, vitamins, multivitamins, vegan and pure foods, powders, oils, and extracts.
- Trusted Brand - Satisfaction Assured: If our Mushroom capsules do not bring noticeable value to you and you don't absolutely love them, your purchase is on us. No Questions Asked. Our world-class customer service wants you to be satisfied with your purchase. Absolutely no risk. The bottle comes with the NutriFlair Satisfaction Pledge for 30 days. Have this powerful immune support and brain and memory booster supplement by your side. Click Add to Cart now and experience the NutriFlair difference.
Bestseller No. 8
Stonehenge Health Dynamic Mushrooms - 100% Fruiting Bodies & Extracts - Lion’s Mane, Chaga, Maitake, Shiitake, Reishi - Nootropic Brain & Immune System Support - No Mycelium - 60 Veggie Capsules
- ✔ CONCENTRATED NON-GMO MUSHROOMS: Contains 5 of the most beneficial mushrooms in Potent EXTRACT forms: Lion's Mane, Reishi, Chaga, Maitake, & Shiitake.
- ✔ 100% FRUITING BODIES & CONCENTRATED EXTRACTS: No mycelium biomass filled with grain or ineffective powders.
- ✔ COGNITIVE HEALTH: Dynamic Mushrooms contains 1,000 mg of Lion’s Mane in a Concentrated Extract that helps support brain health. The equivalent of 4,000 mg of Lion’s Mane powder. *
- ✔ SUPPORT IMMUNE SYSTEM: Helps strengthen your immune system with our concentrated mushroom extract formula year-round. *
- ✔ USA: Manufactured in the USA from the finest globally sourced ingredients, 3rd Party Tested for Quality Assurance
Bestseller No. 9
Ashwagandha and Lions Mane Mushroom Supplement Gummies - Organic - Reishi, Cordyceps, Turkey Tail, Maitake, Shitake, Chaga - Immune Defense, Boosts Cognitive Performance, Vegan, Low Carb
- Advanced Mushroom Blend: Includes Chaga, Maitake, Turkey Tail, Shiitake, Reishi, and Cordyceps; enhanced with lions mane and KSM 66 Ashwagandha; supports immunity, overall health and wellness; promotes mental clarity & focus with traditional medicinal mushrooms
- Carefully Crafted Gummies: Designed to ensure purity, safety and effectiveness; made with high-quality ingredients; crafted under strict manufacturing processes; supports immune & mental performance; provides reliable supplementation for seasonal wellness
- Immune Defense Support: Can serve as an effective immune booster; helps maintain strong and healthy body; formulated with a blend of mushrooms and KSM 66 Ashwagandha known for immune-supporting properties; ideal for maintaining resilience during seasonal changes
- Vegan-Friendly Formula: Non-GMO and gluten-free pectin-based gummies; contain organic ingredients; suitable for vegan diets and plant-based preferences; made with natural ingredients without artificial additives or preservatives
- Delicious Berry Flavor: Offers a natural mixed fruit berry flavor; makes daily supplementation enjoyable; convenient and tasty way to incorporate mushrooms and KSM 66 Ashwagandha into your routine; enhances wellness journey with great taste and vital nutrients
Bestseller No. 10
Lions Mane Mushroom Cognition Capsules (120 Capsules) Lions Mane Mushroom Powder Extract Capsules | Brain Supplement, Brain Vitamins, Focus Supplement
- Lion’s Mane Capsules for Brain & Immune Support: Made using hand-picked Lion’s Mane mushroom extract, our supplement provides impressive benefits to support cognitive function and overall well-being.
- Organic Mushroom Extract: Our mushroom capsules are only made from 100% mushrooms (fruiting bodies), not mycelium grown on grain like most brands. Contains no starch, grains, or mycelium
- Measured Beta-Glucans: Verified by 3rd-party labs, our organic mushroom supplement has >30% beta-glucans per capsule, helping to naturally support your immune system.
- How to Take: Adults take 2 capsules daily. You can also break a few capsules open and add them to your meal or drink. Our mushroom beta glucan supplements are gluten-free, non-GMO, & vegan.
- Mushrooms Made Real: At Real Mushrooms, we produce organic mushroom supplements that support overall health. Our products contain 100% organic mushrooms, carefully sourced and processed for potency & efficacy.