10 Best over the counter estrogen cream (2025)

10 Best over the counter estrogen cream options in 2025 offer effective solutions for those seeking relief from menopausal symptoms and hormonal imbalances. These creams are formulated to provide a convenient and accessible way to supplement estrogen levels without a prescription. Popular choices include brands known for their high-quality ingredients and user-friendly applications. Many of these creams are designed to be easily absorbed, ensuring optimal effectiveness. With a variety of options available, individuals can find the right product to suit their needs, promoting overall well-being and comfort during hormonal changes.

Bestseller No. 1

Estrogen Cream for Menopause Relief

Delicate Menopause Support - We use vegan Phytoestrogen which successfully imitates estrogen in the body thanks to its advanced natural structure. It gently balances estrogen levels, reducing mind & body discomfort related to menopause, and supporting overall wellbeing for a happy, healthy life.
We Are Better - Top American bioidentical estrogen cream contains 200 mg of phytoestrogen per serving - the safer and most effective concentration than any competitor has. We enriched our formula with Ginseng, Green Tea, and Red Clover to promote life balance and Shea Butter with Coconut Oil for skin enhancement.
Made in the USA - Our bio estrogen cream is made and formulated in USA according to strict manufacturing laws and quality protocols. Perfect for all skin types and safe for sensitive areas.
Guarantee Results - Use JNS cream to clear skin up to three times a day for the Guaranteed Result. Can be applied to the breast, lower abdomen, inner thighs, and other sensitive areas. Add to Cart Now and enjoy healthy life balance with the JNS Bioidentical Estrogen Cream!

Bestseller No. 2

Estrogen Cream for Women Menopause Relief: Natural Bioidentical Estrogen Cream with Wild Yam for Hormone Balance, Hot Flashes, Menopause Support-Topical Phytoestrogen Cream for Face, Arms,Abdomen-4 Oz

Relieve Menopause Discomfort: Our Estrogen Cream is thoughtfully crafted to ease the discomfort of menopause, helping to reduce hot flashes, night sweats, and mood swings so you can feel more comfortable and in control during this transition.
Naturally Restore Hormonal Balance: Our natural bioidentical estrogen cream with wild yam gently supports your body’s hormonal balance, helping you regain a sense of calm, well-being, and vitality as you navigate the changes of menopause.
Easy Application: Apply easily to your face, neck, arms, abdomen and other sensitive areas. Our Estrogen Cream absorbs quickly, leaving your skin feeling soft and nourished, while providing essential hormonal support.
Nourishes Dry, Aging Skin: Beyond hormonal support, this cream deeply hydrates and soothes dry, aging skin, helping you maintain a youthful glow and healthy skin during this important phase of life.
Safe and Gentle for Everyday Use: Made with natural, gentle ingredients, Our Natural Phytoestrogen Cream is safe for daily use, even on sensitive skin, offering long-term relief and comfort.

Bestseller No. 3

Estrogen Cream For Women, Natural Bioidentical, Hot Flashes Menopause Relief, Estrogen Cream With Wild Yam, Menstrual Cycle & Body Balance Support, Helps Reduce Hot Flashes, Paraben-Free, Vegan, 3-Month Supply(4 Oz)

Experience Optimal Menopause Support: Our specially-formulated estrogen cream for women is designed to alleviate discomfort related to menopause, balance estrogen levels, and promote overall well-being.
Nature's Best Ingredients: Our estrogen cream is made with MultiEx Phytrogen and other natural ingredients such as cimicifuga racemosa root extract, polygonum cuspidatum root extract, soy isoflavones, and more, to support a more comfortable menstrual cycle during the transition to menopause.
Safe and Effective: Our estrogen cream is vegan, cruelty-free, and gluten-free, making it suitable for all skin types, including sensitive areas. Simply apply the cream three times daily to soft tissue areas such as the face, breast, inner arms, thighs, hands, or bottom of feet for optimal relief.
A Must-Have for All Women: Say goodbye to uncomfortable menopause symptoms and hello to a more comfortable transition. If you have any concerns about our estrogen cream for women, please feel free to contact us. Our customer service team is always available to assist you.

Bestseller No. 4

Estrogen Cream for Women Menopause Relief: Natural Bioidentical Estrogen Cream for Hormone Balance, Hot Flashes, and Menopause Support - Topical Phytoestrogen Cream for Face, Arms and Abdomen - 4 Oz

Relieve Menopause Discomfort: Le’phoqua Estrogen Cream is thoughtfully crafted to ease the discomfort of menopause, helping to reduce hot flashes, night sweats, and mood swings so you can feel more comfortable and in control during this transition.
Naturally Restore Hormonal Balance: Our natural bioidentical estrogen cream gently supports your body’s hormonal balance, helping you regain a sense of calm, well-being, and vitality as you navigate the changes of menopause.
Easy Application: Apply easily to your face, neck, arms, abdomen and other sensitive areas. Le’phoqua Estrogen Cream absorbs quickly, leaving your skin feeling soft and nourished, while providing essential hormonal support.
Nourishes Dry, Aging Skin: Beyond hormonal support, this cream deeply hydrates and soothes dry, aging skin, helping you maintain a youthful glow and healthy skin during this important phase of life.
Safe and Gentle for Everyday Use: Made with natural, gentle ingredients, Le’phoqua Natural Phytoestrogen Cream is safe for daily use, even on sensitive skin, offering long-term relief and comfort.

SaleBestseller No. 5

Estrogen Estriol Cream 175mg of USP Micronized Estriol | Bioidentical Menopause & Menstrual Support | Soy-Free, Gluten-Free, Dairy-Free, Cruelty-Free, Phenoxyethanol-Free | 84 Servings, 3.5oz Pump

THE TOP ESTRIOL CREAM BRAND ON AMAZON: Each 3.5oz pump contains 175mg of Micronized, Certified USP Estriol (~2mg per serving). Each container of Estro-Life Cream lasts approximately 3 months. Vitamin A (Retinol) makes this formula great for skin, too!
HORMONE BALANCE FOR WOMEN: Estro-Life Cream by SMNutrition can help support hormone changes, menopause, and healthy menstrual cycles.* It is highly-absorbable, fragrance-free, and easy to apply.
ATTENTION TO QUALITY: Estro-Life is formulated to be Non-Irritating to skin and bioidentical. It is Non-GMO, Phenoxyethanol-Free, Soy-Free, Gluten-Free, Dairy-Free, Cruelty-Free, PETA.org Certified, and features discreet packaging.
UNIQUE PUMP BOTTLE: Enjoy a longer-lasting product and more hygienic applications! Our 3.5oz. pump makes it easy to control how much cream is dispensed with each use, and the bottle protects your cream in a clean, sealed environment.
THE SMNUTRITION DIFFERENCE: Estro-Life Cream is Third-Party Tested by an ISO 10135 Laboratory. Every batch is manufactured in a facility that is certified GMP compliant with ICMAD standards.

Bestseller No. 6

Nature's Balance - Non-GMO Bio-Identical Estrogen and Progesterone Cream - Free from Petrochemicals, Preservatives, Soy Artificial Fragrances - Made in The USA - Vegan Friendly, 4.2 Ounce

HIGH QUALITY INGREDIENTS - All progesterone and estrogen products are not the same. There are MANY cheaper products on the market, but as with anything else, YOU GET WHAT YOU PAY FOR! Progesterone and Estrogen do over 600 things in your body to keep you healthy. Using a cheap, poor quality hormone products can put you at risk of developing cancer. So don't put your health at risk by using cheap, poor quality hormone products.
We use pharmaceutical grade, bio-identical progesterone in our products. Our Progesterone is designed to mimic the exact progesterone our bodies produce so as to ensure the best and highest quality results. Each 2.1 oz jar contains 1,000 mg of Progesterone and up to 100 servings meaning you get 10 mg per 1/8 tsp.
We use the strongest and most potent form of estrogen in our cream. It's pharmecuedical grade and bio-identical meaning it mimics the natural estrogen your body produces to help you achieve the highest level of results. We use 400 mg per 2.1 oz jar. Each jar contains up to 100 servings meaning you get 4 mg per 1/8 tsp serving
MADE IN THE USA - Both creams are MADE IN THE USA with 100% plant derived ingredients with absolutely no artificial fragrances or toxic petrochemicals or preservatives. Contains no soy, wild yam extract, phytoestrogen, flavones, herbal extracts, or 'phytohormones'. None of these can replace your hormones.
EMPTY JAR GUARANTEE - if you are not completely satisfied with this product, return it at any time for a FULL REFUND!

SaleBestseller No. 7

HOT FLASH & MENOPAUSE SUPPORT: Phyto-Estrogen Cream is a powerful blend of plant compounds to help support women’s balance and comfort during menopause.*
PLANT-BASED BALANCING FORMULA: Made with favorites like Wild Yam, Black Cohosh, Dong-Quai, Red Clover, Licorice, and more.
NO FRAGRANCE OR SYNTHETIC HORMONES: Phyto-Estrogen Cream is made without added fragrances that can irritate sensitive skin. Great for women wanting to support balance without the use of synthetic hormones!
MENSTRUAL CYCLE SUPPORT: By supporting female hormone balance, Phyto-Estrogen cream can help support more comfortable menstrual cycles during the transition to menopause.*
OUR DIFFERENCE: Phyto-Estrogen Cream by SMNutrition is Vegan, Paraben-Free, Non-GMO, Dairy-Free, and Gluten-Free. It is Third-Party Tested by Intertek Labs (2022) and manufactured in a facility that adheres to cGMP guidelines.

Bestseller No. 8

Estrogen Cream for Women Menopause Relief – All Natural Bioidentical Estriol Cream - Hormone Balance BHRT - Pharmacist Formulated, Professional Grade - Made in USA, White

Optimal Menopause Support: Our specially-formulated estrogen cream for women is designed to alleviate discomfort related to menopause Hot Flashes, Perimenopause, PCOS, vaginal dryness, balance estrogen levels, and promote overall well-being.
Nature's Best Ingredients:Contains 500 mg of Bio-Identical, Micronized Estriol USP in a 3.4 oz (100 ml) pump; 5 mg of Estriol per pump (MORE than twice the Estriol of any competing product!) Approximately 90 pumps per bottle!
Safe and Effective: : No Parabens, No Soy, No GMO, and Fragrance-Free. Perfect for all skin types and safe for sensitive areas. Liposome technology for fast absorption and results.
A Must-Have Menopause Relief For Women:: Estriol cream 5mg for women is made in the USA, Micronized Estriol USP; With added Hyaluronic Acid, Niacinamide (Vitamin B3), & Vitamin E. Supplementing Estriol can relieve the effects of Pre-menopause, Perimenopause, menopause, and post-menopause.
Satisfaction: Simply return the product if you do not like it for any reason and we will return your money no questions asked.

Bestseller No. 9

Natural Progesterone Cream for Women, Bioidentical Hormones for Women, Perimenopause & Menopause Cream for Hormonal Balance, 1,000 mg USP Bioidentical Progesterone, Made in the USA, 2 oz (60 mL)

Restore Hormonal Balance Naturally - Enriched with 1,000 mg of bioidentical progesterone, our menopause cream for women mirrors your body’s natural hormones to help ease symptoms of menopause, perimenopause, & menstruation. Feel the harmony return.
Fast-Acting Relief For Menopause - Crafted to soothe hot flashes, night sweats, mood swings & more, this bioidentical hormone cream provides quick comfort by balancing your hormones gently and effectively. Ideal for PCOS support and fertility as well.
Easy and Discreet Application - Our cream for menopause, designed for convenience, allows you simple application. Just apply a small amount twice daily to your wrists, thighs, or abdomen for fast relief. The fast-absorbing smoothly eases symptoms.
Pure, Gentle and Safe For All Skin Types - Made in the USA, our progesterone cream is hypoallergenic, free from GMOs, parabens, and sulfates, thus safe for sensitive skin. Experience the benefits of natural, bioidentical ingredients for smooth care.
Risk-Free, Year-Long Assurance - Begin your journey to hormonal balance with our topical progesterone cream. Backed by a 365-day assurance, we’re committed to ensuring your delight with a product that delivers real results.

Bestseller No. 10

Estrogen Cream, Natural Formula Estrogen Cream for Menopause Relief, Body Balance Support

【Estrogen Cream】Our estrogen cream is designed specifically for women to alleviate the discomfort caused by menopause, balance estrogen levels, and address a variety of other female problems.
【Plant-based Formula】Made with ginseng, green tea and red clover, and fortify the skin with coconut oil and shea butter. Formulated for body balance at midlife.
【Balance at Midlife】It help support women’s balance and comfort during menopause. Complete menopause relief and promote overall health.
【Gentle Yet Effective】Our estrogen cream for women menopause is very mild and non irritating. Fast absorption, fragrance-free, and vegan, suitable for all skin types. Promote beautiful skin!
【Easy to Use】 Simply apply the cream to soft tissue areas such as the face, breasts, inner arms, thighs or soles of the feet. 3 times a day for optimal relief.

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