10 Best mucus cough medicine for adults (2025)

10 best mucus cough medicine for adults in 2025 offer effective relief for those struggling with persistent coughs and congestion. These top-rated options include expectorants like guaifenesin, which help thin mucus, making it easier to expel. Popular brands such as Mucinex and Robitussin lead the market, while natural remedies like honey and herbal syrups gain traction for their soothing properties. Additionally, combination products that target both cough and mucus provide comprehensive relief. Always consult a healthcare professional before starting any new medication to ensure it’s suitable for your specific needs.

SaleBestseller No. 1

Mucinex DM Max Liquid Cough & Cold Medicine For Adults, Cold And Flu Medicine for Excess Mucus Relief, Guaifenesin & Dextromethorphan Expectorant & Decongestant for Adults, Dr Recommended, 6.0 Fl Oz

COUGH COLD AND FLU MEDICINE FOR ADULTS: Mucinex DM Max expectorant & cough suppressant packs a powerful 1..2.. punch with dextromethorphan and Guaifenesin 400mg extended release, providing you with long-lasting relief from mucus congestion and cough.
EXCESS MUCUS RELIEF: Maxium strength multi-symptom relief. Mucinex DM Max is clinically proven to last up to 4hrs and provide relief for chest congestion and make coughs more productive.
EXPECTORANTS AND DECONGESTANTS FOR ADULTS: Mucinex DM Max helps clear lungs of excess mucus and phlegm to help make every day a breath of fresh air. Say goodbye to chest congestion and cough, say hello to excess mucus relief!
EXTENDED RELEASE GUAIFENESIN: Experience 4hr relief with Mucinex DM Max extended-release 400mg guaifenesin and 20mg dextromethorphan HBr in an easier to swallow liquid format.
TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended Brand. Don't be fooled by cheap imitations get the brand that doctors trust and recommend!

Bestseller No. 2

Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant, 14 Tablets

ACTIVE INGREDIENTS: Amazon Basic Care Maximum Strength Mucus Relief DM tablets contain dextromethorphan HBr and guaifenesin; compare to the active ingredients in Maximum Strength Mucinex DM
MAXIMUM STRENGTH: 1200 mg of guaifenesin and 60 mg of dextromethorphan HBr team up to take on your toughest cold
EFFECTIVE: Amazon Basic Care Maximum Strength Mucus-DM clears your chest congestion and eases the intensity of coughing
COUGH SUPPRESSANT: This 12-hour cough medicine contains dextromethorphan HBr for cough relief; it relieves the impulse to cough to help you get to sleep
COUGH EXPECTORANT: Contains guaifenesin to help loosen phlegm so you can cough up that bothersome mucus; makes coughs more productive

SaleBestseller No. 3

Mucinex 12 Hour 1200mg Maximum Strength Guaifenesin Chest Congestion & Mucus Relief, Guaifenesin Expectorant Aids Mucus Removal, Chest Decongestant for Adults, Dr Recommended, 42ct Tablets

EXCESS MUCUS RELIEF: Maximum Strength Mucinex 12hr extended-release tablets pack a powerful punch with 1200 mg guaifenesin expectorant, providing you with long-lasting chest congestion relief
AIDS EXCESS MUCUS REMOVAL: Maximum strength chest congestion relief; Mucinex 12hr lasts up to 12 hours and provides relief for your chest congestion and makes cough more productive
EXPECTORANTS FOR ADULTS: Mucinex helps clear lungs by thinning & loosening mucus; Say goodbye to excess mucus, say hello to chest congestion relief
EXTENDED RELEASE GUAIFENESIN: Experience long-lasting excess mucus relief with Mucinex's 12hr maximum strength extended-release 1200 mg guaifenesin bi-layer tablets with immediate & extended release
TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend

Bestseller No. 4

Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor - 8 Fl Oz Bottle

One 8 fluid ounce bottle of Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor
Non drowsy cough medicine that controls and relieves frequent cough, plus thins mucus to relieve chest congestion
Liquid cough expectorant that's easy to measure and administer
Raspberry flavored cough and chest congestion expectorant provides fast relief
Non drowsy cough suppressant relieves symptoms without slowing you down

Bestseller No. 5

Amazon Basic Care Tussin DM MAX, Cough and Cold Medicine Syrup, Maximum Strength Mucus and Congestion Relief, Non-Drowsy, Raspberry Menthol Flavor, 8 fl oz (Pack of 1)

ACTIVE INGREDIENTS: This cough medicine contains dextromethorphan HBr (a cough suppressant) and guaifenesin (an expectorant) which compare to the active ingredients in Robitussin Maximum Strength Cough and Chest Congestion DM
MAXIMUM STRENGTH: Get maximum strength mucus relief from Amazon Basic Care, a brand you trust; maximum strength claim based on maximum daily dose of active ingredients
COUGH SUPPRESSANT: This cough syrup helps to control your cough; temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold
EXPECTORANT: Clear your excess mucus; each 20mL dose helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes
NON-DROWSY FORMULA: Don't let a nagging cough drag down your day; take this non-drowsy, alcohol-free daytime liquid cough medicine to relieve your cough and cold symptoms; for adults and children 12 and over

Bestseller No. 6

Matys Adult Mucus Cough Syrup for Adults & Children 12 Years & Up, Soothing Relief Ivy With Organic Ingredients & Zinc, 6 Fl Oz

NATURAL COUGH SYRUP: Each ingredient in Maty's Organic Children's Mucus Cough Syrup is thoughtfully chosen for its healing properties. We choose organic ginger, thyme and oregano to thin & loosen pesky mucus. USDA Certified Organic.
IMMUNE BOOSTING INGREDIENTS: Each of Maty's cough syrups have ten immune boosting ingredients in every spoonful. When you have a cough or sore throat, our syrups soothe and coat your throat with organic honey and boost your immune system.
KID FRIENDLY COUGH SYRUP: Get creative with how to take Maty's cough syrups. Since they're made with whole food ingredients, you can use them the same way you'd use honey or maple syrup. Put some in tea, oatmeal, smoothies or even on pancakes!
RETHINK YOUR MEDICINE CABINET: Maty's whole food, alternative health products are made with real ingredients, so you get natural & pure products. Started by a mom who wanted natural remedies for her children, Maty's formulas provide safe, healthy relief.

Bestseller No. 7

Robitussin Adult Maximum Strength Cough + Chest Congestion DM Max (8 fl. oz. Bottle), Cough Suppressant & Expectorant, Raspberry Flavor

One 8 fl oz bottle of Robitussin Maximum Strength Cough and Chest Congestion DM Liquid, Congestion Relief and Cough Medicine, Berry Flavor
Cough suppressant for relief for cough and an expectorant for relief of chest congestion
Maximum-strength formula with expectorant that thins and loosens mucus for productive coughs
Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
Suitable for adults and children 12 years and over

Bestseller No. 8

Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Non-Drowsy Cough Suppressant and Expectorant, Raspberry Flavor, 8 Fl Oz x 2

Two 8 fl oz bottles of Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max, Non-Drowsy Cough Suppressant and Expectorant, Raspberry Flavor
Cough suppressant for non-drowsy control and relief for cough and an expectorant for relief of chest congestion
Maximum-strength cough relief formula with expectorant that thins and loosens mucus for productive coughs
Raspberry flavored, daytime cough medicine delivers fast, effective cough relief
Cough suppressant and liquid expectorant suitable for adults and children 12 years and over

Bestseller No. 9

Mucinex DM 12Hr Maximum Strength Chest Congestion & Cough Medicine For Adults, Cold And Cough Medicine for Excess Mucus Relief, 1200 mg Guaifenesin & 60 mg Dextromethorphan HBr, 7 Bi-Layer Tablets

COUGH & COLD MEDICINE FOR ADULTS: Maximum Strength Mucinex DM 12 hr expectorant & cough suppressant packs a powerful punch with 60 mg dextromethorphan HBr & 1200 mg guaifenesin extended release tablets
EXCESS MUCUS RELIEF: Maximum Strength Mucinex DM 12hr provides relief for your chest congestion & cough, makes coughs more productive, & lasts up to 12 hours
EXPECTORANT FOR ADULTS: Maximum Strength Mucinex DM helps clear lungs of excess mucus and phlegm; Say goodbye to chest congestion and cough, say hello to excess mucus relief with our original bi-layer tablets
EXTENDED RELEASE GUAIFENESIN & DEXTROMETHORPHAN HBr: Experience long-lasting symptom relief with Maximum Strength Mucinex DM 12 hr extended-release 1200 mg guaifenesin and 60 mg dextromethorphan HBr tablets
TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended OTC Expectorant**; Get the brand that doctors trust and recommend

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