10 Best berberine supplement (2025)

Berberine supplements have gained immense popularity for their potential health benefits, particularly in managing blood sugar levels and supporting weight loss. In 2025, the 10 best berberine supplements stand out for their quality, efficacy, and formulation. These top-rated options include brands that prioritize bioavailability and purity, ensuring maximum absorption and effectiveness. Many of these supplements are combined with complementary ingredients like turmeric or probiotics to enhance their benefits. Whether you're looking to improve metabolic health or support cardiovascular function, these berberine supplements offer a reliable choice for health-conscious consumers.

Bestseller No. 1
DOCTOR RECOMMENDED SUPPLEMENTS Berberine Plus 1200mg Per Serving - 120 Veggie Capsules with Royal Jelly
  • Max Potency! 1200 Mg Pure Berberine
  • Effective! Maintain a Healthy System: Berberine HcL (Berberis Aristata) is a compound found in plants such as barberry and goldenseal
  • High Quality! Single Ingredient Supplement: Our Doctor Recommended Pure Berberine is made with only one main ingredient Berberine HCI and vegetable cellulose capsules. With Doctor Recommended it is our mission to make sure you will always get the highest-quality, pure, and safe products that help our customers to live happier and healthier lives
  • Made In USA! Third Party Tested: In a registered laboratory that meets cGMP standards. With NO Artificial ingredients, binders, color additives, chemical, fillers or preservatives. This product is All Natural, Free of Soy, Gluten, Milk, Egg, Wheat, GMOs, Peanuts, Sweeteners, Shellfish
  • Trusted Brand! No Risk - 100% Satisfaction Guarantee: You can be sure that you made a good decision when you buy wellness products from Doctor Recommended Supplements. If you’re not completely satisfied with your purchase, we offer a full refund or a replacement product. It's that simple, guaranteed
SaleBestseller No. 2
Ultra High Strength Berberine HCl 500mg from The Himalayas - Berberine Supplement - 97% Tested Purity Extract - Wild Harvested - Concentrated Berberine 500mg Supplements -90 Veggie Capsules
  • Meet The Next Generation of Berberine 500mg - Toniiq Berberine is a highly purified super concentrated extract, making it one of the most highly concentrated berberine products on the market. Our berberine contains an unprecedented purity level of 97% (most Berberine extracts and Berberine 1200mg supplements won't reveal their purity levels). Higher purity means more of the active compounds that give berberine its powerful health-promoting properties.
  • Wild Harvested from the Mineral-Rich Foothills of the Himalayas -Because our Berberis Aristata is grown in the wild, only the most resilient plants (rich in active components and nutrients) make it to harvest. Toniiq Berberine is produced using an aqueous extraction process to ensure nothing but the highest levels of purity and potency in the finished product.
  • Setting a New Standard for Purity - To ensure that you are getting a high-quality Berberine 500mg supplement, each batch is tested for quality and purity both during and after manufacturing.
  • Quality, First, and Foremost - Toniiq products are produced in a GMP-certified, state-of-the-art manufacturing facility right here in the USA.
  • Each Batch is Individually Tested - We test each batch both ourselves and through a third-party independent laboratory to ensure our ingredients contain the correct standardized level of purity and active ingredients. We also test each batch for any possible additives, contaminants, and impurities to ensure the highest level of quality.
SaleBestseller No. 3
NOW Supplements, Berberine Glucose Support, Combined with MCT Oil for Optimal Berberine Absorption, 90 Softgels
  • Berberine is a natural constituent of herbs such as goldenseal, Oregon grape, and barberry. Clinical studies have demonstrated that berberine helps to support already normal glucose and lipid metabolism.
  • Because berberine is known for its limited bioavailability, this product includes capric acid (C10, a medium-chain triglyceride) to promote optimal absorption and maintenance of gastrointestinal comfort during berberine supplementation.
  • Combined With MCT Oil for Optimal Berberine Absorption
  • A Dietary Supplement
  • General Health
SaleBestseller No. 4
ULTRA HERBS Premium Berberine 12,200MG with Cinnamon, Milk Thistle *USA Made & Test* Promotes Liver Function, Gut Health, Immunity (150 Count (Pack of 1))
  • 14 IN 1 extra strength formula, including: Berberine HCL, Ceylon Cinnamon, Milk Thistle, Dandelion, Bitter melon, Turmeric, Schisandra, Burdock, Fenugreek, Ginger, Artichoke, Licorice, Sea Moss, Black Pepper
  • 150 Capsules - 150 Days supply: Each capsule is equivalent to a total of 12,200MG raw herb powder
  • Optimal Wellness: our Berberine supplement naturally support circulation, liver and gut function, enhancing digestion and aiding weight management
  • EXPERTLY CRAFTED: Ultra Herbs Berberine formula is backed by our commitment to purity and potency.
  • Naturally free from: Gluten, Wheat, Yeast, Milk, Lactose, Soy, Eggs, Tree Nuts, Peanuts, Dairy, Artificial Color & Flavoring & NON-GMO
Bestseller No. 5
THORNE Berberine 1000 mg per Serving - Botanical Supplement - Support Heart Health, Immune System, Healthy GI, Cholesterol - Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings
  • Healthy Body: Berberine is effective in helping to maintain metabolism and cholesterol levels already within a normal range
  • Optimal Wellness: Berberine provides immune function support and promotes a healthy respiratory tract
  • GI Support: Supports beneficial balance in the gut*
  • Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
  • Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of U.S. Olympic Teams
SaleBestseller No. 6
Berberine Supplement - Berberine 1200mg Per Serving - Berberine HCI - Berberine Plus - 60 Berberine Capsules
  • Premium: Our All-Natural Berberine Supplement, made from barberry root extract, has 1200mg of the best Berberine HCI per serving, or 600mg per capsule, consisting of only the highest quality ingredients for energy, glucose and metabolism support.
  • 30 Day Supply - Each bottle lasts for a month to maintain optimal freshness and provide strong immunity support. This berberine supplement for men and women makes the perfect monthly subscription. Stay in stock and save money at the same time!
  • Best Value: We use 1200mg of pure berberine hydrochloride, whereas others are 500mg. Unlike gummies, our premium Berberine capsules provide maximum absorption for glucose support and management without the sugar. Works for vegan or gluten-free diets.
  • 3rd Party Tested: All of our products are 3rd party tested for purity and quality. Our Berberine is made in the USA in our fully certified facility. Luma Nutrition supplements are non-gmo and never include fillers, artificial dyes or heavy metals.
  • Proudly USA: All Luma Nutrition supplements are manufactured in GMP certified facilities in the United States to ensure product safety and quality is always upheld. We are veteran owned and operated and are here to help answer any questions you have.
Bestseller No. 7
Integrative Therapeutics Berberine - 1000–1500 mg Daily - Berberine HCL Supplement for Metabolic Support* - Gluten-Free & Vegan Supplements for Men & Women - 60 Capsules
  • Metabolic Support*: This berberine HCL supplement offers metabolic support for carbohydrate and lipid metabolism*
  • Berberine HCL Supplement: This suppplement supports cellular energy metabolism for men and women
  • Berberine Capsules: This berberine supplement for men and women is bottled and tested in the USA
  • Berberine Metabolic Support: This dietary supplement is gluten-free and vegan; contains no wheat, soy, corn, dairy, artificial colors, flavors, or preservatives
  • About Integrative Therapeutics: Our supplements are trusted by physicians and backed by science; every product is held to our high standards and rigorously tested
SaleBestseller No. 8
(2 Packs) Berberine Supplement Plus Ceylon Cinnamon, Turmeric, Artichoke, Milk Thistle, Black Pepper - 120 Capsules - 4 Months Supply
  • Ingredients: Berberine, Ceylon Cinnamon, Milk Thistle, Turmeric, Artichoke, Black Pepper.
  • How to Take: As a dietary supplement, take one (1) capsule once daily or as directed by your healthcare professional
  • 60 Count (Pack of 2)
  • Easy to swallow 120 total capsules, 5-month supply with 120 servings, 1 capsule serving size.
  • A Dietary Supplement.
Bestseller No. 9
Nutricost Berberine HCl 600mg, 60 Vegetarian Capsules - Gluten Free & Non-GMO
  • 600mg Of Berberine HCl In Every Capsule
  • 60 Vegetarian Capsules Per Bottle
  • Vegetarian Friendly, Non-GMO, and Gluten Free
  • 3rd Party Tested by ISO-Accredited Laboratoreis
  • Made in a GMP Compliant, FDA Registered Facility
SaleBestseller No. 10
Manewu Organic Berberine Supplement - 180 Count Berberine with Ceylon Cinnamon & Citrus Bergamot for We*GHT Health, Gut Health & Immune Support, Berberine 1500mg Complex, 3-Month Supply
  • High-Potency Formula: Each serving of our berberine supplement contains organic berberine 1500mg HCL, a compound derived from plants known for its multifaceted health benefits. This high potency ensures you receive maximum support for your health goals
  • Natural AMPK Activator – Manewu’s berberine supplement with ceylon cinnamon is formulated to support the body's metabolic master switch, AMPK, which can decline with age, helping maintain optimal energy and metabolic function
  • Enhances Gut Health: Our berberine supplement contains 3x berberine 500mg, an ingredient that promotes gut balance. By supporting healthy digestion and nutrient absorption, these berberine capsules help improve overall gut health, which is essential for maintaining energy levels and supporting immune function
  • Synergistic Ingredients: Our Berberine 1500mg capsules are infused with Ceylon Cinnamon and Bergamot for additional antioxidant support. These ingredients work together to amplify the effects of organic berberine hcl, providing additional benefits for overall and metabolic health
  • Vegetarian & Non-GMO: We make your health a top priority with our vegetarian-friendly, non-GMO capsules. Our berberine complex is free of artificial additives and preservatives, ensuring a clean, effective berberine supplement you can trust
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