10 Best eye drops for dry eyes (2025)

10 best eye drops for dry eyes in 2025 offer effective relief for those suffering from discomfort and irritation. These top-rated products include preservative-free options, gel drops for longer-lasting hydration, and formulations enriched with essential nutrients like hyaluronic acid and omega-3 fatty acids. Popular brands such as Refresh, Systane, and TheraTears lead the market with their innovative solutions tailored to various severity levels of dry eye syndrome. With advancements in technology and ingredients, these eye drops not only soothe but also protect the eyes, ensuring optimal moisture and comfort throughout the day.

SaleBestseller No. 1

Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.

Bestseller No. 2

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary
Extended Protection
Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
Reduces both the signs and symptoms of dry eye
Quickly soothe irritated eyes wherever you are

SaleBestseller No. 3

TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, 0.5 fl oz Bottle, 2 Count(Pack of 1)

Get up to 12 Hours of Hydrating Comfort; TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops provide EXTRAordinary relief for dry eyes
Discover TheraTears eye drop; one-of-a-kind silky hydration for dry eyes
Lubricating eye drops for extra dry eyes rehydrate; protect against further irritation and support a natural tear pH level
TheraTears Extra Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
TheraTears corrects the salt imbalance that can cause dry eye symptoms

SaleBestseller No. 4

iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle

iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz bottle.
Unique Formulation: Hydrating polymers form a protective matrix, moisturizing Hyaluronic Acid holds up to 1000x its weight in moisture, and Trehalose (synthetic ingredient also found in desert plants).
Free of Irritating Preservatives: Sterile, safe for use with contact lenses
Patented ABAK Bottle: preservative-free, dispenses drop-by-drop, and does not stream. The ergonomic bottle is easy to open, easy to hold and squeeze.
iVIZIA – We See a Better Way: for healthy, comfortable eyes

SaleBestseller No. 5

TheraTears Dry Eye Therapy Eye Drops for Dry Eyes, 0.5 Fl Oz

TheraTears Dry Eye Therapy - Lubricant Eye Drops provide immediate, long lasting relief of dry eye symptoms
Restores Eyes Natural Balance
Unique hypotonic and electrolyte balanced formula replicates healthy tears
Preservative free in the eye
Convenient, multi-use bottle

SaleBestseller No. 6

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

Fast acting hydration for sensitive eyes
Preservative free tear evaporation protection
Nano droplets for better coverage

SaleBestseller No. 7

TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
TheraTears corrects the salt imbalance that can cause dry eye symptoms
Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness

Bestseller No. 8

LUMIFY Redness Reliever Eye Drops, For Whiter & Brighter Looking Eyes, 0.25 Fl Oz (7.5 mL)

Eye Drops for Red Eyes: LUMIFY significantly reduces redness to help reveal your eyes' natural radiance. From the eye care experts at Bausch and Lomb, LUMIFY works in 1 minute and lasts up to 8 hours
LUMIFY is different: The only OTC drop to contain brimonidine. It selectively targets redness, alleviating some potential side effects associated with other redness relief drops, when used as directed
LUMIFY contains no bleach or dyes. It’s Doctor recommended redness reliever (data on file)
Eye Care Experts at Bausch and Lomb: For over 150 years, we have focused on innovation and quality in eye care products, from contact lenses and solutions to eye drops, ointments, eye vitamins, and more
Amazing Looking Eyes: We understand how important eyes are. And despite all the eye creams, mascara, eyeliners and eyeshadows, if your eyes are red, you won’t look your best

Bestseller No. 9

Optase Dry Eye Intense Drops - Preservative Free Eye Drops for Long Lasting Relief - Artificial Tears to Relieve Severe Dry Eye Symptoms - Multidose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses

MOISTURIZE AND PROTECT: Made of glycerin and quality ingredients, Optase Dry Eye Intense Drops mix with the natural oils needed to protect your tears and hydrate your eyes to improve tear quality
PRESERVATIVE FREE: Optase Intense Eye Drops is the only product of its kind to provide a preservative free combination of ingredients designed to treat dry eye patients in a unique multi-dose bottle
MODERATE TO SEVERE DRY EYE RELIEF: The long lasting formulation of Optase Intense provides comfort for dry eye and post operative patients. And it is contact lens safe, providing relief when needed
ADVANCED BOTTLE TECHNOLOGY: A convenient multi-use drop bottle with advanced technology maintains sterility over 3 months without preservatives. Avoid the hassle of individual vials while on the go
COMPLETE DOCTOR RECOMMENDED EYE CARE RELIEF: OPTASE is the expert recommended 3-step regimen to help tackle the cause and symptoms of Dry Eyes, Blepharitis and Meibomian Gland Dysfunction (MGD)

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