10 Best stool softener (2025)

10 Best stool softeners (2025) offer effective relief for those struggling with constipation. These products are designed to ease bowel movements by increasing moisture in the stool, making it softer and easier to pass. Top contenders include brands like Colace, Miralax, and Dulcolax, each providing unique formulations to suit different needs. Natural options, such as psyllium husk and flaxseed oil, are also gaining popularity for their gentle approach. With a variety of choices available, individuals can find the perfect stool softener to promote digestive health and enhance overall well-being in 2025.

Bestseller No. 1
Amazon Basic Care Stool Softener Laxative, Docusate Sodium 100 mg, Softgels, For Constipation Relief, 100 Count
  • STOOL SOFTENER LAXATIVE, Amazon Basic Care Docusate Sodium 100 mg, Softgels contain docusate sodium 100 mg, the physician recommended stool softener OTC active ingredient (of U.S. physicians surveyed by an independent market research firm). Compare to the active ingredient in Colace
  • THESE SOFTGELS work gently to soften stools and generally produce a bowel movement in 12 to 72 hours. Here is your answer for an effective stool softener laxative to provide gentle and predictable constipation relief
  • GENTLE AND PREDICTABLE constipation relief for adults and children ages 2 years and over. This effective stool softener laxative comes in a convenient softgel and is gluten free.
  • THIS STOOL SOFTENER is stimulant free for convenient, predictable relief of occasional constipation symptoms, such as: fewer than 3 bowel movements per week; dry, hard stools; difficult or painful bowel movements; feeling that not all stool has passed.
  • DOCUSATE SODIUM IS the physician recommended stool softener OTC active ingredient (of U.S. physicians surveyed by an independent market research firm).
Bestseller No. 2
HealthA2Z® Stool Softener | Docusate Sodium 100mg | Red & White Capsules | Dependable | Gentle Constipation Relief (400 Counts)
  • It provides a gentle but effective relief from occasional constipation and bowel irregularity.
  • Active ingredient Docusate Sodium Stool Softener 100mg softgels works by increasing the amount of water the stool absorbs in the gut, thereby softening the stool and making it easier to pass.
  • Our stool softener is stimulant free and should produce a bowel movement in 12-72 hours.
  • For the prevention of dry, hard stools. This product generally produces a bowel movement within 12 to 72 hours.
  • Adults and children 12 years and older: Take 1-3 softgels daily, preferably at bedtime. Children 2 to under 12 years of age: Take 1 softgels daily, preferably at bedtime. Children under 2 year of age: ask a doctor.
Bestseller No. 3
Kirkland Signature Stool Softener 100 mg, 400 Softgels
  • Compare Stool Softener to Colace!
  • Kirkland laxative also have a stool-softener effect!
  • Stool-Softener gently provides relief from constipation!
  • Gently stimulates the muscles of the colon!
  • VALUE PACK!! 2 BOXES!! 400 SoftGels!!!
SaleBestseller No. 4
Colace Regular Strength Stool Softener for Gentle Effective Constipation Relief, No.1 Doctor Recommended Stool Softener Brand, 100 mg Docusate Capsules, 30 Count
  • Colace Regular Strength capsules gently soften dry, hard and painful stool - a safe, stimulant-free and gentle option for a #2 that’s easy to do.
  • Number 1 Doctor recommended stool softener brand. Provides gentle, dependable and effective relief from occasional constipation in 12 to 72 hours.
  • Stimulant-free: Colace’s active ingredient, docusate sodium, allows water and fats to get into the stool, which helps soften it and makes passing it more comfortable.
  • Gently softens stools: Colace Regular Strength Stool Softener relieves many symptoms of occasional constipation, including infrequent or irregular bowel movements, straining during bowel movements & hard dry stools.
  • Occasional constipation relief during pregnancy & for new moms (post-partum). (If pregnant or breastfeeding, ask a health professional before use.)
SaleBestseller No. 5
Colace Clear Stool Softener Soft Gel Capsules Constipation Relief 50mg Docusate Sodium Doctor Recommended 28ct
  • Colace Clear is a stool softener available in a clear formulation that is dye-free and a lower strength; It is our lowest dose for gentle relief from occasional constipation.
  • COMFORTABLE EFFECTIVE RELIEF: Colace Clear Stool Softener Soft Gels effectively treat occasional constipation; including constipation associated with certain medical conditions; It is a safe; gentle option; without any stimulant laxatives.
  • GENTLY SOFTENS STOOLS: Docusate sodium; the active ingredients in Colace Clear; allows water and fats to get into the stool to help soften fecal material & make bowel movements more comfortable; Allows for a gentle relief of occasional constipation.
  • RELIEVES SYMPTOMS OF OCCASIONAL CONSTIPATION: Including infrequent or irregular bowel movements; straining during bowel movements and hard dry stools; Reduces straining of bowel movements associated with occasional constipation.
  • STIMULANT FREE; DYE FREE; AND LOWER STRENGTH: For gentle; dependable; effective relief from occasional constipation; Colace Clear Stool Softener soft gels are a great choice for occasional constipation.
Bestseller No. 6
HealthA2Z® Stool Softener | Docusate Sodium 100mg | Red Capsules | Dependable | Gentle Constipation Relief (400 Counts (Pack of 1))
  • It provides a gentle but effective relief from occasional constipation and bowel irregularity.
  • Active ingredient Docusate Sodium Stool Softener 100mg softgels works by increasing the amount of water the stool absorbs in the gut, thereby softening the stool and making it easier to pass.
  • Our stool softener is stimulant free and should produce a bowel movement in 12-72 hours.
  • Adults and children 12 years and older: Take 1-3 softgels daily, preferably at bedtime. Children 2 to under 12 years of age: Take 1 softgels daily, preferably at bedtime. Children under 2 year of age: ask a doctor.
SaleBestseller No. 7
Dulcolax Stool Softener Laxative Liquid Gel Capsules, Gentle Constipation Relief for Hard, Dry Stools, Docusate Sodium 100 mg, 100 Count
  • Includes: One (1) 100-count box of Dulcolax Stool Softener Laxative Liquid Gel Capsules with docusate sodium 100 mg
  • Gentle constipation relief: Dulcolax stool softeners provide gentle relief for painful, hard, dry stools
  • Predictable relief: These stool softener laxatives relieve occasional constipation and irregularity in as little as 12 to 72 hours
  • Works in harmony with your body: Made with docusate sodium, Dulcolax stool softeners work naturally with the water in your body to hydrate stool, making it softer and easier to pass
  • On-the-go convenience: Pack these stool softener laxative gel capsules in your travel essentials to help you get back to being regular when stress and overindulgence slow you down
SaleBestseller No. 8
Equate - Stool Softener 100 mg, 140 Capsules (Compare to Colace) (1)
  • Compare to Colace active ingredient.
  • Docusate Sodium 100mg.
  • Relieves Constipation.
  • Gentle and Effective.
  • Stimulant free for comfortable relief.
Bestseller No. 9
Major Docusate Sodium 250 mg - Extra Strength Stool Softener Laxative Softgels for Constipation Relief - Gentle Stool Softeners for Women, Men, and Kids Ages 12+ - 100 Softgels (2 Pack)
  • EFFECTIVE LAXATIVES FOR ADULTS AND KIDS: Keep things moving with Major's extra-strength Docusate Sodium 250 mg laxative softgels, a trusted solution for occasional constipation relief.
  • RELIEF WHEN YOU NEED IT: Get back to feeling like yourself with our specially formulated anti-constipation medicine. These stool softener softgels generally support a bowel movement within 12-72 hours, ensuring relief when you need it most.
  • GENTLE ON YOUR SYSTEM: These laxative softgels deliver gentle, targeted relief that softens the stool for smoother and easier passage, encouraging bowel movement. For adults and children ages 12 years and over, take 1 softgel daily.
  • QUALITY FORMULATION: We maintain high standards of care through strict regulatory compliance to deliver carefully formulated, effective stool softeners. With a 250 mg Docusate Sodium formulation, our softgels are a gentle solution for aiding with constipation.
  • MAJOR PHARMACEUTICALS: At Major Pharmaceuticals, we believe wellness should be accessible to everyone. We pride ourselves on our legacy of delivering quality OTC and vitamin supplements.
SaleBestseller No. 10
Kirkland Signature Stool Softener 100 mg, 400 Softgels
  • Compare to the Active Ingredient in Colace
  • Docusate Sodium 100 mg
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