10 Best stain remover for clothes (2025)

10 best stain removers for clothes in 2025 offer powerful solutions for tackling tough stains effectively. These top-rated products include options like OxiClean MaxForce, Zout Laundry Stain Remover, and Shout Advanced Gel, each designed to target specific stains such as grease, wine, and grass. Eco-friendly choices like Biokleen and Molly's Suds are also gaining popularity for their gentle yet effective formulas. With innovations in stain-fighting technology, these removers not only lift stains but also protect fabric integrity, ensuring your clothes look fresh and vibrant. Choose the right stain remover to keep your wardrobe in pristine condition.

Bestseller No. 1

Shout Active Enzyme Laundry Stain Remover Spray, Triple-Acting Formula Clings, Penetrates, and Lifts 100+ Types of Everyday Stains - Prewash Spray 22oz

What You'll Get: One 22oz spray bottle of Shout's Prewash Active Enzyme Stain Remover Spray
Everyday formula: works on a wide range of stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
Clings, Penetrates, & Lifts: 50x more concentrated than in-wash powered when applied directly to stain
Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
Spray, Rub, and Wash: our formula let's you treat the toughest stains and wash up to a week later

Bestseller No. 2

Miss Mouth's Messy Eater Stain Treater Spray - 4oz 3 Pack Stain Remover - Newborn & Baby Essentials - No Dry Cleaning Food, Grease, Coffee Off Laundry, Underwear, Fabric

Bestseller No. 3

Shout Advanced Stain Remover Gel for Clothes Laundry, Ultra Concentrated Gel with Built-in Scrubber Brush for Deep Set-In stains, 8.7oz

What You'll Get: One 8.7oz bottle of Shout Advanced Ultra Concentrated Stain Remover Gel with Built-in Scrubber Brush technology
Tackling Tough Stains Easy: this super-concentrated thick laundry stain remover gel is made specifically to treat some of your toughest set-in stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
Household Staple: a great addition to your laundry supplies, this stain remover is tough on stains but gentle on fabric, available in a convenient bottle with a built-in laundry brush for stains that works the enzymes deep into the fabric fibers
Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
Squeeze, Rub, Wash, Done: our formula let's you treat stains and wash up to a week later

Bestseller No. 4

Grandma's Secret Spot Remover Laundry Spray - Chlorine, Bleach and Toxin-Free for Clothes - Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains - 16 oz & 2 oz Combo, DuoPack

✅ HARSH ON STAINS NOT THE FABRIC: The toxin-free stain remover formula removes just the stains, not the beautiful color of your clothes. Our effective yet gentle stain remover for clothes does not contain bleaching agents or leave dirt-attracting residues, so spot remover should not harm your fabric. You can use Grandmas spot remover worry-free on your expensive investment.
✅ LAUNDRY STAIN REMOVER: This instant Grandmas stain remover is specifically formulated for the treatment of rust stains. Try fabric stain remover on those stains that have aged in, or ones that have gone through the washing machine already. The best part is that fabric cleaner is concentrated. The clothes stain remover formula has no bleach, chlorine or phosphates added & grandma stain remover leaves behind a pleasant citrus fragrance.
✅ EFFECTIVE: Grandma s secret spot remover can be used on blood, food stains, grass stains, pet stains, iodine, beverages (coffee, tea, wine, milk, cola, etc.), crayon, uncured latex paint, chocolate, raw egg, candle wax, heavy grime, ketchup, grease, oil stains, most shoe polishes, much more and the Grandma secret spot remover formula works in all water temperatures.
✅ BABY STAIN REMOVER: No matter how adorable the baby is, keeping your sweet cheeks clean is a challenge. The baby stain remover for laundry goes to work to remove everything from diaper leaks to your baby food mishaps.
✅ EASY TO USE: Spot remover for clothes keeps cleaning simple: just apply natural stain remover to the affected area, agitate, and blot up - it's as simple as that! Stains are completely gone with clothes stain remover.

Bestseller No. 5

Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains - 22oz Spray

What You'll Get: One 22oz spray bottle of Shout's Advanced Laundry Stain Remover Gel
Formulated for heavy duty stains: this thick gel stain remover is made specifically to treat difficult stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
Best Shout Formula: made with 70% more stain-fighting power compared to Shout Triple-Acting
Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
Spray, Rub, Wash, and Done: our formula let's you treat stains toughest stains and wash up to a week later

Bestseller No. 6

OxiClean Max Force Laundry Stain Remover Spray, 2 fl oz, 2PK

These convenient 2 fl oz bottle 2-pack of OxiClean Max Force Laundry Stain Remover Spray tackles your stubborn and dried-in laundry stains
OxiClean Max Force stain spray lets you pretreat stains now, then wash up to seven days later for cleaning that fits your schedule
Powerful laundry spot remover for oil, grease, make-up, blood, grass, soil, clay, ink, food, drinks, and kid and baby stains
Laundry stain remover for clothes is 100 percent dye free and chlorine free, and safe for use on all machine-washable whites and colored fabrics, even kid and baby clothes
Spray directly on stains until saturated, let stand five minutes or up to seven days before washing with detergent in the warmest water garment will accept. For whiter, brighter clothes, add OxiClean Versatile Stain Remover to washer per label directions

Bestseller No. 7

Tide Pen Stain Remover for Clothes, Tide To Go Pen, Instant Stain Remover Pen & Spot Cleaner, Portable & Travel-Friendly, Works on Food & Drink Stains, Fits in Purses & Bags, 3 Count (Pack of 1)

Tackle Fresh Stains on the Go: Don't let food and drink spills ruin your day. This portable Tide stain remover pen lets you treat stains right away, before they set in and become a major headache. Keep this Tide to go pen wherever you need it most for stain emergencies. Brought to you by Nehemiah Manufacturing.
Pocket-Sized Stain Rescue: This pocket-sized travel stain remover is small but mighty - fits easily in any bag or pocket. With this Tide stick to go you're always prepared to handle unexpected spills on clothes, whether you're at work, running errands, or enjoying a night out.
Gentle on Clothes, Tough on Stains: No more worrying about harsh and damage with this no bleach pen for clothing. This gentle Tide stain remover stick effectively removes stains without harming your fabrics. Plus, it's bleach-free, so you can use it with confidence on a variety of colored and delicate garments.
Works on Many Food & Drinks: Spilled ketchup on your shirt? Coffee stain on your pants? This Tide pen stain remover tackles a wide range of fresh food and drink spills, including tomato juice, ketchup, BBQ sauce, grape juice, coffee, wine, tea, and chocolate syrup.
Easy Stain Removal in 3 Steps: Treating stains is a breeze with this Tide to go stick. Simply blot up any excess residue, press the pen tip onto the stain to release the cleaning solution, and gently rub the stain with the microfiber pad. Repeat if needed for stubborn stains. No mess, no fuss, just clean clothes with this Tide pens.

Bestseller No. 8

Shout Advanced Laundry Stain Remover Gel for Clothes Laundry, Breaks down stubborn, dried-in, and tough stains - 22oz Spray (Pack of 3)

What You'll Get: Three 22oz spray bottle of Shout's Advanced Laundry Stain Remover Gel
Formulated for heavy duty stains: this thick gel stain remover is made specifically to treat difficult stains from food, drinks, makeup, grass, dirt, red wine, blood, and more
Best Shout Formula: made with 70% more stain-fighting power compared to Shout Triple-Acting
Quick & Easy To Use: works on all machine-washable whites and colored fabrics, and works in all water temperatures and in HE and standard washers
Spray, Rub, Wash, and Done: our formula let's you treat stains toughest stains and wash up to a week later

Bestseller No. 9

OxiClean MaxForce Laundry Stain Remover Spray, 12 Fl. oz.

Combines 5 types of Stain Fighters to help you get out more of your toughest dried-in stains the 1st time!
Great on grass and blood, grease and oil, food stains, soil and clay
Tackles the toughest dried-in stains
Treat your clothes now and then wash up to a week later
Contains 12 fluid ounces

Bestseller No. 10

Grandma's Secret Spot Remover - Chlorine, Bleach, and Toxin-Free Stain Remover - Stain Remover for Clothes - Fabric Stain Remover Removes Oil, Paint, Blood and Pet Stains -3 Pack of 2 Ounce

✅ HARSH ON STAINS NOT THE FABRIC: The toxin-free stain remover formula removes just the stains, not the beautiful color of your clothes. Our effective yet gentle stain remover for clothes does not contain bleaching agents or leave dirt-attracting residues, so spot remover should not harm your fabric. You can use Grandma’s spot remover worry-free on your expensive investment.
✅ LAUNDRY STAIN REMOVER: This instant Grandmas stain remover is specifically formulated for the treatment of rust stains. Try fabric stain remover on those stains that have aged in, or ones that have gone through the washing machine already. The best part is that the fabric cleaner is concentrated. The clothes stain remover formula has no bleach, chlorine, or phosphates added & grandma stain remover leaves behind a pleasant citrus fragrance.
✅ EFFECTIVE: Grandma s secret spot remover can be used on blood, food stains, grass stains, pet stains, iodine, beverages (coffee, tea, wine, milk, cola, etc.), crayon, uncured latex paint, chocolate, raw egg, candle wax, heavy grime, ketchup, grease, oil stains, most shoe polishes, much more and the Grandma’s secret spot remover formula works in all water temperatures.
✅ BABY STAIN REMOVER: No matter how adorable the baby is, keeping your sweet cheeks clean is a challenge. The baby stain remover for laundry goes to work to remove everything from diaper leaks to your baby food mishaps.
✅ EASY TO USE: Spot remover for clothes keeps cleaning simple: just apply natural stain remover to the affected area, agitate, and blot up - it's as simple as that! Stains are completely gone with clothes stain remover.

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