10 best protein powders for weight gain in 2025 offer a variety of options to help you achieve your fitness goals. These protein powders are designed to provide high-calorie content, essential nutrients, and a delicious taste, making it easier to increase your daily caloric intake. Popular choices include whey protein, casein, and plant-based blends, each catering to different dietary preferences. Brands like Optimum Nutrition, BSN, and MuscleMilk lead the market with their effective formulations. Whether you're a bodybuilder or simply looking to gain weight, these protein powders can support your journey towards a healthier, stronger physique.
SaleBestseller No. 1
Dymatize Super Mass Gainer Protein Powder, 1280 Calories & 52g Protein, Gain Strength & Size Quickly, 10.7g BCAAs, Mixes Easily, Tastes Delicious, Gourmet Vanilla, Gourmet Vanilla, 6 Pound (Pack of 1)
- 10.7 grams of BCAAs as building blocks, including 5.1g Leucine, as building blocks to help activate Muscle Protein Synthesis
- 1280 calories and 245g carbs per serving to help even the hardest gainers pack on mass
- 52g protein per serving (a blend of fast and slow digesting proteins) to fuel your muscles throughout the day
- 14 vitamins and minerals to support muscle recovery.
SaleBestseller No. 2
Optimum Nutrition Serious Mass, Weight Gainer Protein Powder, Mass Gainer, Vitamin C and Zinc for Immune Support, Creatine, Vanilla, 6 Pound (Packaging May Vary)
- HIGH CALORIE WEIGHT GAINER: More than 1,200 calories per 2-scoop serving
- 50 grams of blended protein per 2-scoop serving
- Over 250 grams of carbohydrates per 2-scoop serving
- 22 vitamins and minerals including Vitamin C, Vitamin D, and Zinc to provide immune support
- With over 20 vitamins and minerals including Vitamin C and Zinc to provide immune support
Bestseller No. 3
GNC Pro Performance Weight Gainer Protein Powder | Increase Muscle Mass | Banned Substance Tested | Vanilla Ice Cream | 6 Servings
- FUEL BIGGER ATHLETIC GOALS: Stack the scale in your favor and choose from three decadent flavors of a great-tasting blend of protein powder, naturally occurring BCAAs, carbohydrates, and added medium chain triglycerides (MCT).
- INCREASE YOUR PROTEIN INTAKE BEFORE OR AFTER TRAINING: GNC Pro Performance Weight Gainer delivers 50g of a protein blend designed to digest over time and help ensure essential amino acids (EAA) are readily available for muscles.
- POWER UP FOR A BIG DAY WITH 700 CALORIES: High-quality protein fuels muscles and 115-117g of a dual carbohydrate system preserves and replenishes energy stores.
- WORKOUTS WITH MCT AND BCAA: Weight Gainer’s added MCT is quickly absorbed by the body for use as energy and BCAA may help reduce muscle breakdown during exercise.
- CHOOSE A BANNED SUBSTANCE-TESTED WEIGHT GAINER: Unlike most gainers with proprietary blends, GNC Pro Performance Weight Gainer is certified Banned Substance Tested and designed to deliver the right nutrition for your goals.
Bestseller No. 4
Body Fortress Super Advanced Whey Protein Powder, Cookies N’ Creme, 60g Protein & 12g BCAAs Per 2 Scoops, Muscle Gain & Recovery, Immune Support with Vitamins C & D, 1.78lbs (Packaging May Vary)
- 60G OF PROTEIN PER 2 SCOOPS – Power your workouts with 60g of high-quality whey protein per 2-scoop serving, designed to support muscle gain, strength, and post-workout recovery.
- 12G OF BCAAs FOR MUSCLE RECOVERY – Packed with 12g of Branched Chain Amino Acids (BCAAs) to fuel muscle repair, reduce soreness, and optimize recovery after intense training.
- IMMUNE SUPPORT FORMULA – Fortified with Vitamins C & D and Zinc to help maintain a healthy immune system while you achieve your fitness goals.
- DELICIOUS COOKIES N’ CREME FLAVOR – Enjoy the creamy and indulgent taste of cookies and cream in a protein shake that mixes easily with water or milk for a satisfying treat.
- CLEAN AND NUTRITIOUS – Body Fortress Whey Protein is low in sugar, gluten-free, and contains no aspartame, making it a great addition to clean diets and active lifestyles.
SaleBestseller No. 5
Mass Gainer MuscleTech 100% Mass Gainer Protein Powder Protein Powder for Muscle Gain Whey Protein + Muscle Builder Creatine Supplements Vanilla, 5.15 Pound (Pack of 1)
- MASS GAINER PROTEIN POWDER – 100% Mass Gainer is specially formulated for performance athletes looking to increase their dietary protein, carbohydrates and overall calorie intake. 100% Mass Gainer is a premium weight gainer for increased size and strength
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- SUPERIOR WEIGHT GAINER – MuscleTech 100% Mass Gainer is packed with high-quality protein and mass-producing calories, plus muscle builder creatine monohydrate, a proven anabolic driver for faster mass and strength gains. This superior formula will help you get bigger and stronger
- NUTRIENT-DENSE MUSCLE BUILDER – With 100% Mass Gainer, you’ll reach musclebuilding milestones more efficiently. The high-quality protein and easily digestible carbs can deliver 1,500 clean calories when mixed with 2 cups of skim milk
- CREATINE MONOHYDRATE – Reimagine the limits of size and strength, as 100% Mass Gainer only uses pure HPLC-tested creatine. Scientific studies have shown that it helps replenish ATP stores in the body for enhanced performance, more muscle and strength
SaleBestseller No. 6
Optimum Nutrition Gold Standard 100% Whey Protein Powder, Double Rich Chocolate, 2 Pound (Packaging May Vary)
- Gold Standard 100% Whey - 24g of protein per serving to help build and maintain muscle when taken over time with regular resistance training
- 5.5g of aturally occurring branched chain amino acids (BCAA and 11g of naturally occurring essential amino acids (EAAs) per serving to support muscle recovery
- Anytime formula – great before or after exercise, between meals, with a meal, or any time of day when you need extra protein
- Optimum Nutrition is the World's #1 Sports Nutrition Brand*
- Banned substance tested and the highest quality control measures so you feel comfortable and confident consuming the product
Bestseller No. 7
Premier Protein Powder, Vanilla Milkshake, 30g Protein, 1g Sugar, 100% Whey Protein, Keto Friendly, No Soy Ingredients, Gluten Free, 17 Servings, 23.3 Ounces
- Sweet and smooth, this vanilla flavored protein powder helps pack in the nutrition you rely on every day while delivering indulgent taste like a bowl of creamy vanilla ice cream
- 30g Protein per serving, with all the essential amino acids and 100% of protein from Whey to feed your muscles and curb your hunger
- Guilt free yum: 1g Sugar, 3g Carbs, 150 Calories and Low Fat; No Soy Ingredients, Gluten Free
- Each tub comes with 17 servings and a scoop – just add water for smooth, decadent but easy post-workout recovery
- Mix, Bake, Blend – recreate your favorites smoothie, pancakes, muffins, cookies, donuts, brownies, or protein bars
SaleBestseller No. 8
Dymatize ISO100 Hydrolyzed Protein Powder, 100% Whey Isolate, 25g of Protein, 5.5g BCAAs, Gluten Free, Fast Absorbing, Easy Digesting, Fruity Pebbles, 20 Servings
- Dymatize ISO100 Fruity Pebbles Protein Powder (20 Servings)
- Scientifically formulated with fast-digesting hydrolyzed whey protein isolate. If your goal is gains in muscle size and strength, ISO100 is your perfect partner
- 25 grams of protein, which includes 5.5 grams of branched-chain amino acids (BCAAs), & 2.6 grams of Leucine per serving
- 1 gram of fat and less than 1 gram of sugar per serving.
- Easy on the stomach and gluten free, with less than 0.5g of Lactose; sweeteners like sucralose, steviol glycosides are present
SaleBestseller No. 9
Optimum Nutrition Serious Mass, Weight Gainer Protein Powder, Mass Gainer, Vitamin C and Zinc for Immune Support, Creatine, Chocolate, 6 Pound (Packaging May Vary)
- HIGH CALORIE WEIGHT GAINER: More than 1,200 calories per 2-scoop serving
- 50 grams of blended protein per 2-scoop serving
- Over 250 grams of carbohydrates per 2-scoop serving
- With over 20 vitamins and minerals including Vitamin C and Zinc to provide immune support
- MORE VERSATILITY: Using an electric blender, add fresh or frozen fruits, peanut butter, nuts, and other calorie dense foods to boost your weight gain potential
SaleBestseller No. 10
Muscle Milk Gainer Protein Powder, Vanilla Creme, 32g Protein, 5 Pound
- Contains one (1) 5 pound cannister (about 14 servings) of Muscle Milk Pro Series Gainer Protein Powder Supplement. Packaging may vary. Shaker bottle sold separately
- KEY FEATURES – Based on 1 serving, Muscle Milk Pro Series Gainer contains 32g high-quality protein, 109g carbs, 650 calories, 2g MCTs, and an excellent source of 20 vitamins and minerals
- VERSATILE AND EASY-TO-MIX – Muscle Milk Pro Series Gainer dissolves easily in water; just mix 4 scoops into 10-16 fluid ounces of water using a shaker bottle. Shaker bottle sold separately
- SCIENCE BEHIND PROTEIN – Provides a blend of high-quality slow releasing and fast releasing proteins to help increase amino acid levels