10 Best numbing cream (2025)

10 Best numbing cream options for 2025 offer effective pain relief for various procedures, from tattoos to minor surgeries. These creams are formulated with potent ingredients like lidocaine and benzocaine, ensuring quick and lasting numbness. Top contenders include products like Dr. Numb, Numbify, and Hush, each praised for their fast-acting formulas and skin-friendly properties. Users appreciate the ease of application and minimal side effects, making these creams ideal for both professionals and at-home use. As the demand for pain management solutions grows, these 10 best numbing creams stand out for their reliability and effectiveness in providing comfort during painful experiences.

Bestseller No. 1

Ebanel 5% Lidocaine Numbing Cream, Pain Relief Cream Burn Itch Cream, 1.35 Oz 1-Pack, Topical Anesthetic Cream Maximum Strength with Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment

FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor cuts, minor scrapes, minor burns, sunburn, scrapes, and minor skin irritations. It also works for mosquito bite itch relief, bug bite itch relief, insect bite relief, postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

Bestseller No. 2

Curist 5% Lidocaine Cream Topical Pain Relief - Numb Quickly & Effectively with 5% Lidocaine Numbing Cream - (1 Pack - 2 oz Jar)

LIDOCAINE 5% PAIN CREAM | Experience deep pain relief with the strongest formulation of topical lidocaine available OTC.
MADE IN THE USA | A fast pain relief, anti itch, and numb cream - made with the highest quality ingredients without the typical pharmacy mark-up.
TREAT, NUMB & SOOTH ALL-IN-ONE | Our soothing, numbing cream provides fast relief from pain, itching, burning, discomfort & irritation by blocking the nerves and desensitizing. Numbing relief for hemorrhoids and other anorectal issues.
CURIST PAIN RELIEF CREAM | Stronger tha Aspercreme 4% Lidocaine, which is typically used for muscle pain and as a tattoo numbing cream.
EASY ACCESS JAR | Light, whipped formula for easy application. Get numbing relief at a fraction of the cost. For external use only.

Bestseller No. 3

Nupharmisto 6 Hours Tattoo Numbing Cream (2oz/ 60ml), Maximum Strength Painless Tattoo Numbing Cream, Numbing Cream for Tattoos Extra Strength with 5x Numbing, Emu Oil and Arnica. 2oz/ 60ml

LASTING RELIEF: Our Tattoo Numbing cream is specially formulated to provide long-lasting numbing, and relief itching, soreness, burning, and reduce tattoo swelling. helps to desensitize the skin, allowing you to feel more comfortable during your procedure.
EFFECTIVE HEALING PROPERTIES: Our tattoo numbing cream contains a blend of powerful ingredients, including Arnica, and Emu Oil, to help speed up the healing process of your tattoo. Our Tattoo Numbing Cream penetrates the skin to deliver these ingredients, helping to soothe, moisturize, and heal your skin. This means less scabbing and less chance of infection, resulting in a beautiful, vibrant tattoo.
MULTIPURPOSE: Our numbing cream can be used for a variety of procedures, including tattooing, piercing, microblading, micro needling, Botox, laser hair removal, and waxing. This means you can enjoy the benefits of our cream for all your cosmetic and beauty needs.
ODOR-FREE, OIL-FREE & NON-GREASY: Our Tattoo Numbing Cream is easy to apply and remove, leaving no mess behind. It's vegan friendly, cruelty-free, and contains no harsh chemicals, making it safe for all skin types.
EASY TO USE: Our tattoo numbing cream is simple to use. Just wash the area to be treated, apply the numbing cream, wrap it in plastic for 50-60 minutes, and wait for full absorption. We recommend patch testing before use to ensure compatibility with your skin.

Bestseller No. 4

Tattoo Numbing Cream Maximum Strength: 6 Hours Painless Tattoo Numbing Cream - Extra Strength Numbing Cream for Tattoos Piercing Waxing 50g/1.7oz

Powerful Long-Lasting Relief: Experience up to 6 hours of painless tattooing with our Maximum Strength Numbing Cream. This extra-strength formula is designed to effectively numb the skin, allowing you to get through the entire session with minimal discomfort. Ideal for both new tattoos and touch-ups, our cream ensures a more enjoyable and relaxed experience.
Painless Tattoo Numbing Cream: Our Extra Strength Painless Tattoo Numbing Cream desensitizes the skin for a pain-free tattooing experience. Stay relaxed and comfortable throughout your session. Walk into your appointment with confidence, knowing you're ready for a smooth, painless tattoo!
Effective Healing Properties: Our tattoo numbing cream contains a blend of powerful ingredients, including chrysanthellum indicum extract and portulaca oleracea extract, to help speed up the healing process of your tattoo. Our Tattoo Numbing Cream penetrates the skin to deliver these ingredients, helping to soothe, moisturize, and heal your skin. This means less scabbing and less chance of infection, resulting in a beautiful, vibrant tattoo.
Multipurpose for All Your Needs: Beyond just tattoos, our numbing cream is a versatile ally for a range of beauty and cosmetic procedures. From piercings and waxing to microblading and laser hair removal, our cream offers reliable pain relief. Whether you're a professional artist or a first-timer, this cream is your go-to for any skin-numbing need.
Safe for All Skin Types: Our Tattoo Numbing Cream is suitable for all skin types and is gentle enough for sensitive skin. With a special blend of emollients and moisturizers, it not only numbs but also hydrates the skin, promoting a smoother and more comfortable tattoo application process. Say goodbye to the pain and hello to a worry-free tattoo experience.

Bestseller No. 5

Tattoo Numbing Cream by Signature with 20X More Lidocaine Strength - Best Numbing Cream for Tattoo Before & Aftercare - Painless Tattoo with More Numbing Power (10 Grams, 0.35 Ounce (Pack of 1)

Formulated with Lidocaine to provide 20X more skin numbing

Bestseller No. 6

Tattoo Numbing Cream(1.41fl.oz/ 40g),6-8 hours Maximum Strength,Painless Tattoo Numbing Cream,Contains vitamin E, Mint, Licorice,Suitable for Tattoos, Piercings, Hair Removal, Microneedle,Hemorrhoids

Tattoo cream:Our super powerful tattoo cream used to Relieve itching, burning, and reduce tattoo swelling allows you to enioy the entire tattoo process comfortably,Lasts up to 6-8 hours.
Suitable for a variety of scenarios：Tattoo cream can be used for a variety of procedures, including tattooing, piercing,micro needling, Botox, laser hair removal, and waxing. This means you can use our products in any beauty scene and enjoy the safe and comfortable process that comes with special effects tattoo cream,get beautiful in enjoyment.
Multi-purpose Tattoo Cream:Our cream for tattoos extra strength is very versatile and can be used include mosquito bites, piercings microneedle, waxing
Odorless, oil-free, non-greasy:Our tattoo cream is easy to apply and remove, leaving no trace,contains no harsh chemicals,Suitable for all skin types.
Easy to use: Wash the area with warm water, wipe it dry, apply the tattoo cream, wrap it tightly with plastic wrap, wait for 50-60 minutes, take off the plastic wrap, wipe the cream ,then you can start tattoo work.

SaleBestseller No. 7

Ebanel 5% Lidocaine Numbing Cream, 2-Pack Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment

FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb cream with Allantoin, clinically proven to temporarily relieve pain, burning, itching, and discomfort, reduces inflammation and soreness in local and anorectal areas
5% Lidocaine Cream Maximum Strength - This pain relief anti itch cream provides immediate relief for minor aches, minor cuts, minor scrapes, minor burns, sunburn, scrapes, and minor skin irritations. It also works for mosquito bite itch relief, bug bite itch relief, insect bite relief, postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
Enhanced Liposomal Deep Penetrating Skin Numbing Cream - Best efficacy, fast-acting & long-lasting. It begins numbing in 3-5 minutes, peaks after 20-25 minutes, and lasts 1 hour from its peak. Numbing performance may vary depending on the thickness of the skin area and individual metabolism
Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply before, during, and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy application and no-mess removal
Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing

SaleBestseller No. 8

8 Hours Maximum Strength Tattoo Numbing Cream,5% Lidocaine Numbing Cream,Painless Tattoo Numbing Cream for Tattooing, Piercing, Waxing & Injections,Hemorrhoid Treatment

High-Efficiency Numbing Formula for Rapid Pain Relief: Contains 5% lidocaine, which quickly penetrates the skin to provide immediate numbing effects, relieving minor pain, cuts, scrapes, burns, sunburns, and other skin discomforts. Especially suitable for treating sensitive areas during procedures like tattoos, piercings, and cosmetic treatments.
Versatile Applications for a Wide Range of Procedures: Our numbing cream is designed for various beauty and medical procedures, including tattoos, laser hair removal, microneedling, Botox injections, waxing, and more. Whether you're a professional or a home user, you'll benefit from up to 8 hours of continuous numbing, ensuring a pain-free experience.
Additional Care for Various Skin Issues: Beyond numbing for procedures, It also works for mosquito bite itch relief, bug bite itch relief, insect bite relief, postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
ODOR-FREE, OIL-FREE & NON-GREASY: Our Tattoo Numbing Cream is easy to apply and remove, leaving no mess behind. It's vegan friendly, cruelty-free, and contains no harsh chemicals, making it safe for all skin types.
EASY TO USE: Our tattoo numbing cream is simple to use. Just wash the area to be treated, apply the numbing cream, wrap it in plastic for 30-45 minutes, and wait for full absorption. We recommend patch testing before use to ensure compatibility with your skin.

Bestseller No. 9

Tattoo Numbing Cream Maximum Strength(50g), 6 Hours Maximum Strength, Numbing Cream for Waxing Brazilian Wax, Best Tattoo Numbing Cream, Numbing Cream for Tattoos, Numbing Cream for Waxing

QUICK-ACTING & LONG-LASTING: Tattoo numbing cream maximum strength is specially designed to alleviate burning, itching, and soreness, reducing tattoo swelling for up to 6 hours. Using our numbing cream for tattoos enables you to complete your tattoo session uninterrupted, without the need to pause or slow down.
PAINLESS TATTOO NUMBING CREAM: Our tattoo numbing cream extra strength is created to ensure a comfortable and stress-free tattooing experience. Picture a painless tattooing or waxing experience thanks to our best tattoo numbing cream, which effectively desensitizes the skin.
POTENT HEALING INGREDIENT: Infused with aloe vera, our numbing cream for waxing brazilian wax accelerates the healing process. Our numbing cream for waxing deeply penetrates the skin, delivering this key ingredient to soothe, hydrate, and support the healing process. Our numbing cream is the best tattoo numbing cream!
MULTI-FUNCTIONAL: Our numbing cream for tattoos is ideal for a range of cosmetic procedures, including tattooing, piercing, laser hair removal, and waxing. Discover the benefits of our cream for all your beauty needs. It's an excellent choice for numbing cream for tattoos extra strength.
SUITABLE FOR ALL SKIN TYPES: Our tattoo numbing cream is easy to apply, non-greasy, and leaves no residue. It's vegan-friendly, cruelty-free (not tested on animals), and free from harsh chemicals. We recommend performing a patch test on a small area of skin prior to use to ensure there is no adverse reaction.

Bestseller No. 10

HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 1.75 Oz

MAXIMUM STRENGTH RELIEF — Provides temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backaches, strains, sprains and bruises; apply directly to the skin
FAST-ACTING LIDOCAINE — Containing 4% lidocaine, this cream works by desensitizing the nerves, effectively numbing the pain where the cream is applied with no irritation and no burning
NON-GREASY FORMULA — Non-greasy formula glides on smooth; safely apply every 6-8 hours, up to 3x daily
SUPPORT AND INSTRUCTION — Follow the detailed use instructions, as well as the warnings and cautions, before use; use only as directed, instructions are easy to follow and use
Compare to Aspercreme with Lidocaine active ingredients

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