Lysine supplements are gaining popularity in 2025 for their numerous health benefits, including supporting immune function and promoting muscle recovery. The 10 best lysine supplements this year include brands like NOW Foods, Solgar, and Jarrow Formulas, known for their high-quality formulations and bioavailability. Other top contenders are Nature's Way, Garden of Life, and KAL, which offer vegan-friendly options. Additionally, brands like Thorne Research and Pure Encapsulations provide premium, allergen-free lysine supplements. With a variety of forms available, including capsules and powders, these products cater to diverse dietary needs and preferences, making it easier than ever to incorporate lysine into your routine.
SaleBestseller No. 1
NOW Foods Supplements, (L-Lysine Hydrochloride) 1,000 mg, Double Strength, Amino Acid, 100 Tablets
- DOUBLE STRENGTH VEGAN TABLETS/ESSENTIAL AMINO ACID: Lysine is an essential amino acid that must be obtained through diet or supplementation.
- SUPPORTS COLLAGEN SYNTHESIS*: Necessary for the production of all proteins in the body and is required for the maintenance of the structural proteins collagen and elastin.*
- CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Non-GMO, Vegan/Vegetarian, Nut Free, Made without Gluten, Dairy Free, Egg Free, Kosher
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
- Packaged in the USA by a family owned and operated company since 1968.
SaleBestseller No. 2
Nature Made L-Lysine 1000 mg, Dietary Supplement, 60 Tablets, 60 Day Supply
- Protein synthesis support supplement: Contains one 60 count bottle of Nature Made L-Lysine 1000 mg Tablets for a 60-day supply
- L Lysine is an essential amino acid that supports protein synthesis
- This L Lysine supplement provides 1000 mg of Lysine in just one daily tablet
- Adults take one of these Lysine tablets daily with water and a meal
- This Lysine supplement has no color added, no artificial flavors, no preservatives, and is gluten free
Bestseller No. 3
Pure Encapsulations L-Lysine - Essential Amino Acid Supplement for Immune Support & Gum, Lip Health* - with L-Lysine HCl - 90 Capsules
- Essential Amino Acid: L-Lysine is one of several essential amino acids that cannot be manufactured by the body; supports body's natural defenses*
- Lysine Supplement for Immune Support: L-Lysine provides nutritional support to help maintain immune function and immune system*
- Natural Defense Support: These essential L-Lysine capsules maintain arginine production and support the body's natural immune defenses*
- Pure Quality: Our supplements are made with premium ingredients sourced from trusted suppliers and guided by nutritional experts, then manufactured and tested to verify potency and purity
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
Bestseller No. 4
Quantum Health Super Lysine+ / Advanced Formula Lysine+ Immune Support with Vitamin C, Echinacea, Licorice, Propolis, Odorless Garlic (180 Tablets), Packaging may vary
- ADVANCED L-LYSINE IMMUNE BOOST - Super Lysine+ provides L-Lysine, Vitamin C, deodorized garlic, and Echinacea for immune support and lip health, plus propolis and licorice root for powerful antioxidant support.
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- THE MANY BENEFITS OF LYSINE - A building block of protein, Lysine benefits include immune system support, promoting collagen growth, & supporting lip health. For optimal results, use with Quantum Health Super Lysine+ Cold Sore Ointment.
- AWARD-WINNING LYSINE POWER FORMULA - Taste for Life Immunity Essentials Specialty Award (2015), Taste for Life Supplement Essentials Award (2013), and Better Nutrition Best of Supplements Award (2008).
- FROM A TRUSTED LEADER IN THE NATURAL PRODUCTS INDUSTRY – Quantum Health's first product was a Lysine cold sore treatment. Since then, Quantum Health has led in sourcing only the highest quality, research-supported ingredients for our supplements.
Bestseller No. 5
NOW L-Lysine 500 mg,250 Capsules
- ESSENTIAL AMINO ACID: L-Lysine is an essential amino acid, which means that it cannot be manufactured by the body and must be obtained through the diet or by supplementation.
- SUPPORTS HEALTHY CONNECTIVE TISSUE AND CALCIUM ABSORPTION: Lysine is necessary for the production of all protein in the body including hormones, enzymes, and antibodies, as well as carnitine and collagen, which is the structural protein forming all connective tissue such as skin, tendon, and bone. L-Lysine also plays a major role in calcium absorption.
- CLASSIFICATIONS/CERTIFICATIONS: Non-GMO, Dairy Free, Egg Free, Made without Gluten, Nut Free, Soy Free, Vegan/Vegetarian
- Non-GMO
- A Dietary Supplement
SaleBestseller No. 6
Bronson L-Lysine Defense Immune Support Complex 1500 MG L-Lysine Plus Olive Leaf, Garlic, Vitamin C and Zinc - Non-GMO, 90 Vegetarian Capsules
- L-Lysine Defense Complex: L-Lysine is an essential amino acid that is obtained through foods and supplementation. It’s thought that L-Lysine helps to maintain healthy production of the amino acid L-Arginine. L-Lysine helps to keep L-Arginine within a healthy range and support overall immune health.*
- Plus Olive Leaf, Garlic, Vitamin C & Zinc: L-Lysine combined with key additional immune support ingredients for superior coverage. Combining natural herbal ingredients, such as Olive Leaf and Garlic, which have been used throughout history in various cultures to support immune health.* Additionally includes Vitamin C and Zinc to help replenish the body with essential nutrients to help maintain a healthy immune system.*
- Highest Quality Formula: Laboratory tested NON-GMO. All Bronson products are tested in our state-of-the-art cGMP registered facility in New York.
- Trusted Since 1960: The pioneers of Bronson Vitamins were a group of pharmacists who witnessed the benefits of vitamins and mineral supplementation firsthand with their patients. Bronson Vitamins have been consistently mentioned by top medical professionals since our inception in 1960.
Bestseller No. 7
THORNE Lysine - Essential Amino Acid for Skin Health, Energy Production, and Immune Function - 500 mg - 60 Capsules
- Wound Healing: Supports the healing of unhealthy skin by promoting collagen formation
- Immune Health: Lysine’s nutritional support helps the body maintain its natural defenses and promotes healthy gum and lip tissues
- Skin And Bone Health: Promotes collagen formation for healthy and elastic skin, while also promoting calcium absorption for strong bones and teeth
- Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
SaleBestseller No. 8
Solgar L-Lysine 1000 mg, 250 Tablets - Enhanced Absorption and Assimilation - Promotes Integrity of Skin and Lips - Collagen Support - Amino Acids - Non-GMO, Vegan, Gluten Free - 250 Servings
- Solgar L-Lysine 1000mg Provides An Essential Amino Acid The Body Cannot Produce; Amino acids are the building blocks of protein; They are needed for several internal body functions and help produce energy
- Supports Healthy Skin Tissue; L Lysine 1000mg Tablets help promote the integrity of skin and lips; Lysine is used by the body to produce collagen
- Optimal Amino Absorption; The free form lysine in this dietary supplement promotes optimal absorption and assimilation because it is easy to digest
- Non GMO And Gluten Free; Solgar L-Lysine Tablets are suitable for vegans and vegetarians; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, and color
- The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
SaleBestseller No. 9
Vegan Lysine Supplement by MaryRuth's | Ultra Absorption | Lysine 500mg | Collagen Formation Support | Immune Support Supplement | Health & Wellness | Non GMO | Gluten Free | 30 Servings
- 500 mg Lysine Liposomal: Enjoy this essential amino acid to support your health and wellness in a delicious Snickerdoodle liposomal! Provide your body with tissue support with just half a tablespoon per day.
- Vegan L Lysine: L-Lysine is an essential amino acid that our bodies need, but cannot make on their own. Amino acids are the building blocks of protein!
- Essential Amino Acid: As an amino acid, lysine supports tissue health by helping collagen formation. Enjoy 500 mg L-Lysine per serving in this delicious Snickerdoodle (vanilla and cinnamon) flavored liposomal!
- Ultra Absorption: Liposomes are tiny spherical structures that have a protective outer layer and an inner cavity to hold and transport substances such as vitamins or other nutrients to the body. These tiny structures encapsulate these substances and can lead to ultra absorption!
- For Most Lifestyles: MaryRuth's Lysine Liposomal is Non-GMO, Vegan, Dairy Free, Soy Free, Sugar Free, Made in a GMP Facility. Clean Label Project Verified. B Corp Certified.
Bestseller No. 10
Nutricost L-Lysine 1000mg Per Serving, 250 Servings, 500 Capsules - Gluten Free, Non-GMO, 500mg Per Capsule
- 500mg of Premium L-Lysine Per Capsule, 1000mg Serving
- 250 Servings (500 Capsules) of This Essential Amino Acid
- Serving Size: 1-2 Capsules
- Non-GMO, Gluten Free. Lid may be either blue or white
- Made in a GMP Compliant, FDA Registered Facility.