10 Best hemorrhoid cream to shrink (2025)

Hemorrhoid cream to shrink discomfort and promote healing is essential for those suffering from this common condition. In 2025, the 10 best options include products like Preparation H, Anusol, and Tucks Medicated Cooling Pads, known for their soothing properties. Other top contenders feature natural ingredients, such as witch hazel and aloe vera, which provide relief without harsh chemicals. Brands like RectiCare and HemAway offer targeted formulas that effectively reduce swelling and irritation. Choosing the right hemorrhoid cream can significantly enhance comfort and expedite recovery, making daily activities more manageable for those affected.

Bestseller No. 1

Preparation H Hemorrhoid Symptom Treatment Cream (0.9 Ounce Tube), Maximum Strength Multi-Symptom Pain Relief with Aloe

Includes one 0.9 Ounce tube of Preparation H Maximum Strength Hemorrhoid Pain Relief cream.
The only over the counter hemorrhoid treatment cream with maximum strength pramoxine for multi-symptom relief.
Proprietary hemorrhoid cream blend with vitamin E, panthenol and soothing aloe.
Provides rapid hemorrhoid relief from pain, burning, itching and discomfort.
Preparation H cream rapidly relieves external hemorrhoid symptoms.

SaleBestseller No. 2

Doctor Butler’s Hemorrhoid & Fissure Ointment – Hemorrhoid Treatment and Hemorrhoid Cream with Lidocaine and Phenylephrine HCI for Fast Acting Relief of Pain, Swelling, Discomfort, and Itching (1 oz.)

LEAVE THE PAIN BEHIND: Doctor Butler’s hemorrhoid ointment and anorectal lidocaine cream was developed by a Board Certified Proctologist to ensure our ingredients offer the best hemorrhoid treatment for women and men.
LIDOCAINE NUMBING CREAM: This hemorrhoid relief and fissure treatment formula works as a numbing cream for rapid relief from hemorrhoids. Our hemorrhoids cream also features Phenylephrine, a vasoconstrictor to help reduce swelling.
HEAL, SOOTHE and PROTECT: Discover instant relief with this paraben free hemorrhoidal cream that also features herbs, essential oils and minerals, and amino acids for added healing solutions. Aloe vera extract, ginseng extract and horse chestnut offer further benefits with skin protectant properties for external hemorrhoid care.*
LEADING HEMORRHOIDS TREATMENT: Join more than 200,000 satisfied new customers who purchased Doctor Butler’s hemorrhoid products for multi symptom relief over this year. Feel the relief of fissures and hemorrhoid pain, discomfort, burning, itching and swelling.*
MADE IN THE USA: Doctor Butler’s ointments, creams, and sprays are manufactured in the USA under rigorous quality controls to ensure the safe & effective use of all our products. We have also partnered with Leaping Bunny to maintain cruelty free standards across our brand.

Bestseller No. 3

Doctor Butler's Advanced Hemorrhoid & Fissure Ointment – Lidocaine Hemorrhoid Treatment and Fissure Treatment Extra Strength Formula, Heals and Provides Fast Pain and Itch Relief* (1.5 oz.)

LEAVE THE PAIN BEHIND: Doctor Butler’s hemorrhoid ointment was developed by a Board Certified Proctologist to ensure the use of the best ingredients for hemorrhoid relief and fissure treatment.
FIND FAST RELIEF: This lidocaine cream based formula works as a numbing cream to quickly alleviate your pain associated with hemorrhoids.* We created a hemorrhoids cream for both pain and itch relief that works quickly and efficiently.
HEAL AND SOOTHE: This hemorrhoid cream is made with lidocaine to numb and soothe your skin, along with its unique formula of organic herbs, essential oils, minerals an amino acid, bringing you added healing solutions. It’s also made paraben-free!
LONGER-LASTING PROTECTION: The Advanced formula features lidocaine ointment to protect inflamed tissue with glycerin to reduce friction and pain, for rapid relief and longer-lasting coverage. Added ingredients like ginseng extract and horse chestnut offer you a natural skin protectant and anti-inflammatory properties.*
MADE IN THE USA: Doctor Butler’s products are manufactured in the USA and are produced in our facility. Rigorous quality control of ingredients is done and a safety seal is added to prove the SAFE & EFFECTIVE use of our products. We have also partnered with Leaping Bunny to maintain cruelty free standards.

SaleBestseller No. 4

Recticare Advanced Hemorrhoidal Cream: Advanced Treatment to Shrink & Soothe Hemorrhoids - Itch, Pain, Burn Relief - 30g Hemorrhoidal Cream with Lidocaine

FAST, EFFECTIVE, SOOTHING RELIEF – RectiCare Advanced Hemorrhoidal Cream alleviates the pain, itch, and discomfort associated with hemorrhoids while shrinking and protecting the swollen tissue.
MAXIMUM STRENGTH WITHOUT A PRESCRIPTION – Contains 5% Lidocaine – clinically proven to deaden the nerve endings in skin and surrounding tissue, providing temporary pain relief. The 0.25% Phenylephrine reduces the swelling of hemorrhoidal tissue.
DUAL ACTION FORMULA – RectiCare Advanced Hemorrhoidal Cream both soothes and protects. This cream also contains white petroleum and mineral oil which provides a protective coating over inflamed tissue between applications.
THE DOCTORS CHOICE – RectiCare Advanced Cream is recommended by colon and rectal surgeons for temporary relief of discomfort from a variety of anorectal disorders including hemorrhoids and anal fissures.
CHILD PROOF SAFETY CAP - Recticare Advanced is manufactured with a child proof safety cap. Please know that the nature of this cap inhibits the manufacturer from placing a seal under the cap.

Bestseller No. 5

Mayinglong Musk Hemorrhoids Ointment (3 x 10g Tubes), 30g - Maximum Strength Formula for Hemorrhoidal Fast Relief, Soothes Itching, Burning & Discomfort - Fast-Acting Treatment to Shrink Swelling

INGREDIENTS USED IN ASIA SINCE 1582. An effective ointment for hemorrhoids, Mayinglong Hemorrhoid Ointment is now available in the US, distributed by Trifecta Pharmaceuticals USA.
HOW IT WORKS: Shrinks swollen Hemorrhoid tissue. The zinc carbonate (in calamine) has been shown to reduce the size of blood vessels both for internal and external hemorrhoids
EASY TO USE & VERY COST EFFICIENT - This hemorrhoid ointment is the most affordable Hemorrhoid Treatment and with our hemorrhoids relief system, you'll easily be hemorrhoids free in a few weeks. You will save lots of money by not having to go to the doctor.
REDUCES HEAT AND INFLAMMATION The borates in Borax, compounds in Bovis Calculus and proteins in Margarita all work to reduce heat and swelling, commonly seen in hemorrhoid
RELIEVES HEMORRHOIDS: As heat, swelling and the inflammatory reaction are reduced, the associated pain and discomfort subsides.

SaleBestseller No. 6

Nikzon Hemorrhoid Treatment Cream, Vasoconstrictor & Anesthetic, Fast Soothing Relief from Pain, Itching, Burning & Inflammation, 0.9 oz

HEMORRHOID RELIEF CREAM: Nikzon Hemorrhoidal Cream provides fast and soothing temporary relief from local pain, discomfort, itching and inflammation associated with hemorrhoids
DOCTOR RECOMMENDED INGREDIENTS: Doctors recommend the double action hemorrhoids treatment cream for the effective reduction of itching and inflammation. Nikzon gives you a double effect of anesthetic and vasoconstrictor to aid with the pain and swelling
HOW IT WORKS: The hemorrhoid cream features ingredients like phenylephrine HCl (vasoconstrictor) that relieves the swelling in the anorectal area while Pramoxine HCl (anesthetic) helps relieve the pain and itching of hemorrhoids
RELIEVES BOWEL MOVEMENT DISCOMFORT: This external hemorrhoid treatment cream temporarily numbs the irritated, inflamed anorectal area for a less painful bowel movement
HOW TO USE: Apply a thin layer of the cream to affected area up to four times a day on cleansed and dry skin - in the morning, at night, and after bowel movements. Consult a physician if condition doesn't improve in 7 days

SaleBestseller No. 7

Amazon Basic Care Hemorrhoid Ointment, Hemorrhoid Treatment, Pain Relief, Relieves Burning, Itching and Discomfort, 2 ounce (Pack of 1)

ACTIVE INGREDIENTS: This product contains mineral oil 14%, petrolatum 74.9%, phenylephrine HCl 0.25%, protectants and vasoconstrictor, which compare to the active ingredients in Preparation H.
EFFECTIVE HEMORRHOID OINTMENT: Hemorrhoid Ointment gives fast temporary relief from the painful burning, itching, and discomfort of hemorrhoids.
TYPES OF HEMORRHOIDS: External hemorrhoids are located under the skin around the anus. Internal hemorrhoids develop in the lower rectum.
FAST-ACTING, HEMORRHOID PAIN RELIEF: This hemorrhoid treatment temporarily shrinks swollen hemorrhoidal tissue and relieves burning. You are more likely to get hemorrhoids if you: strain during bowel movements, have chronic constipation or diarrhea, or eat foods that are low in fiber.
HEMORRHOID OINTMENT: Temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful.

Bestseller No. 8

Preparation H Hemorrhoid Ointment, Itching, Burning and Discomfort Relief - 1 Oz Tube

One 1 oz tube of Preparation H Hemorrhoid Ointment
Preparation H Hemorrhoid Ointment helps relieve symptoms of both internal and external hemorrhoids
Pain and itch relief ointment quickly relieves itching, burning and discomfort
Skin treatment helps shrink swollen tissue caused by hemorrhoids
For effective hemorrhoid care, use Preparation H Medicated wipes to cool and cleanse the area before using this hemorrhoid relief ointment

Bestseller No. 9

Boiron HemCalm Ointment for Hemorrhoid Relief of Pain, Itching, Swelling or Discomfort - 1 oz

Paraben-free formula targets external hemorrhoids.
Can be used with hemcalm Suppositories for internal hemorrhoids and hemcalm tablets.
Can be applied externally up to four times a day.
Safe to use at the First Sign of Symptoms before discomfort becomes more disruptive.
Recommended for everyone ages 12 and up.

Bestseller No. 10

Musk Hemorrhoids Ointment 10 Grams - Maximum Strength Formula for Hemorrhoidal Fast Relief, Soothes Itching, Burning & Discomfort - Fast-Acting Treatment to Shrink Swelling

INGREDIENTS USED IN ASIA SINCE 1582: An effective ointment for hemorrhoids, Mayinglong Hemorrhoid Ointment is now available in the US, distributed by Trifecta Pharmaceuticals USA.
HOW IT WORKS: Shrinks swollen Hemorrhoid tissue. The zinc carbonate (in calamine) has been shown to reduce the size of blood vessels both for internal and external hemorrhoids
HOW TO PRONOUNCE: How to Pronounce? Ma (as short for mom, “ma”), Ying (as in Ying and Yang), Long (with a long O, “looooong”)
REDUCES HEAT AND INFLAMMATION: The borates in Borax, compounds in Bovis Calculus and proteins in Margarita all work to reduce heat and swelling, commonly seen in hemorrhoid
RELIEVES HEMORRHOIDS : As heat, swelling and the inflammatory reaction are reduced, the associated pain and discomfort subsides.

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