10 Best hemorrhoid cream (2025)

10 Best hemorrhoid cream options for 2025 offer effective relief for those suffering from discomfort and pain. These creams are formulated with soothing ingredients like witch hazel, aloe vera, and hydrocortisone to reduce inflammation and promote healing. Popular choices include Preparation H, Anusol, and Tucks Medicated Cooling Pads, each providing unique benefits. Many of these creams also feature natural extracts to enhance comfort and minimize irritation. With advancements in formulation, users can expect faster relief and improved results, making these top-rated hemorrhoid creams essential for managing symptoms effectively in the coming year.

Bestseller No. 1

Preparation H Hemorrhoid Symptom Treatment Cream (0.9 Ounce Tube), Maximum Strength Multi-Symptom Pain Relief with Aloe

Includes one 0.9 Ounce tube of Preparation H Maximum Strength Hemorrhoid Pain Relief cream.
The only over the counter hemorrhoid treatment cream with maximum strength pramoxine for multi-symptom relief.
Proprietary hemorrhoid cream blend with vitamin E, panthenol and soothing aloe.
Provides rapid hemorrhoid relief from pain, burning, itching and discomfort.
Preparation H cream rapidly relieves external hemorrhoid symptoms.

SaleBestseller No. 2

Amazon Basic Care Hemorrhoid Ointment, Hemorrhoid Treatment, Pain Relief, Relieves Burning, Itching and Discomfort, 2 ounce (Pack of 1)

ACTIVE INGREDIENTS: This product contains mineral oil 14%, petrolatum 74.9%, phenylephrine HCl 0.25%, protectants and vasoconstrictor, which compare to the active ingredients in Preparation H.
EFFECTIVE HEMORRHOID OINTMENT: Hemorrhoid Ointment gives fast temporary relief from the painful burning, itching, and discomfort of hemorrhoids.
TYPES OF HEMORRHOIDS: External hemorrhoids are located under the skin around the anus. Internal hemorrhoids develop in the lower rectum.
FAST-ACTING, HEMORRHOID PAIN RELIEF: This hemorrhoid treatment temporarily shrinks swollen hemorrhoidal tissue and relieves burning. You are more likely to get hemorrhoids if you: strain during bowel movements, have chronic constipation or diarrhea, or eat foods that are low in fiber.
HEMORRHOID OINTMENT: Temporarily protects the inflamed, irritated anorectal surface to help make bowel movements less painful.

SaleBestseller No. 3

Doctor Butler’s Hemorrhoid & Fissure Ointment – Hemorrhoid Treatment and Hemorrhoid Cream with Lidocaine and Phenylephrine HCI for Fast Acting Relief of Pain, Swelling, Discomfort, and Itching (1 oz.)

LEAVE THE PAIN BEHIND: Doctor Butler’s hemorrhoid ointment and anorectal lidocaine cream was developed by a Board Certified Proctologist to ensure our ingredients offer the best hemorrhoid treatment for women and men.
LIDOCAINE NUMBING CREAM: This hemorrhoid relief and fissure treatment formula works as a numbing cream for rapid relief from hemorrhoids. Our hemorrhoids cream also features Phenylephrine, a vasoconstrictor to help reduce swelling.
HEAL, SOOTHE and PROTECT: Discover instant relief with this paraben free hemorrhoidal cream that also features herbs, essential oils and minerals, and amino acids for added healing solutions. Aloe vera extract, ginseng extract and horse chestnut offer further benefits with skin protectant properties for external hemorrhoid care.*
LEADING HEMORRHOIDS TREATMENT: Join more than 200,000 satisfied new customers who purchased Doctor Butler’s hemorrhoid products for multi symptom relief over this year. Feel the relief of fissures and hemorrhoid pain, discomfort, burning, itching and swelling.*
MADE IN THE USA: Doctor Butler’s ointments, creams, and sprays are manufactured in the USA under rigorous quality controls to ensure the safe & effective use of all our products. We have also partnered with Leaping Bunny to maintain cruelty free standards across our brand.

Bestseller No. 4

Preparation H Hemorrhoid Ointment, Itching, Burning and Discomfort Relief - 1 Oz Tube

One 1 oz tube of Preparation H Hemorrhoid Ointment
Preparation H Hemorrhoid Ointment helps relieve symptoms of both internal and external hemorrhoids
Pain and itch relief ointment quickly relieves itching, burning and discomfort
Skin treatment helps shrink swollen tissue caused by hemorrhoids
For effective hemorrhoid care, use Preparation H Medicated wipes to cool and cleanse the area before using this hemorrhoid relief ointment

Bestseller No. 5

Doctor Butler's Advanced Hemorrhoid & Fissure Ointment – Lidocaine Hemorrhoid Treatment and Fissure Treatment Extra Strength Formula, Heals and Provides Fast Pain and Itch Relief* (1.5 oz.)

LEAVE THE PAIN BEHIND: Doctor Butler’s hemorrhoid ointment was developed by a Board Certified Proctologist to ensure the use of the best ingredients for hemorrhoid relief and fissure treatment.
FIND FAST RELIEF: This lidocaine cream based formula works as a numbing cream to quickly alleviate your pain associated with hemorrhoids.* We created a hemorrhoids cream for both pain and itch relief that works quickly and efficiently.
HEAL AND SOOTHE: This hemorrhoid cream is made with lidocaine to numb and soothe your skin, along with its unique formula of organic herbs, essential oils, minerals an amino acid, bringing you added healing solutions. It’s also made paraben-free!
LONGER-LASTING PROTECTION: The Advanced formula features lidocaine ointment to protect inflamed tissue with glycerin to reduce friction and pain, for rapid relief and longer-lasting coverage. Added ingredients like ginseng extract and horse chestnut offer you a natural skin protectant and anti-inflammatory properties.*
MADE IN THE USA: Doctor Butler’s products are manufactured in the USA and are produced in our facility. Rigorous quality control of ingredients is done and a safety seal is added to prove the SAFE & EFFECTIVE use of our products. We have also partnered with Leaping Bunny to maintain cruelty free standards.

Bestseller No. 6

Globe (3 Pack) Hemorrhoid Cream, Relief with Aloe, (1.8 Ounce Tube) Relief from Hemorrhoids, Piles, Itching, Burning, Discomfort, & More

GENTLE SOOTHING: Globe Hemorrhoid Cream focuses on relieving hemorrhoids as comfortably possible. We use fast numbing action to reduce itching, burning caused by Hemorroids. We use natural soothing aloe vera to help keep skin healthy while reducing swelling.
RELIEF AND PROTECTION: This hemorrhoid product uses Phenylephrine HCl, Pramoxine HCl, and White Petrolatum to reduce size and soothe Hemorroidal symptoms while numbing. Our formula uses glycerol to form a protective layer around the hemorrhoid to guard against friction.
EFFECTIVE RELIEF: Globe's Hemorrhoid Ointment relieves symptoms for both internal and external hemorrhoids and piles. The soothing creme gives relief from swelling, flare-ups, and discomfort. Just compare our active ingredients to Preparation H.
FASTER AND EASIER: Globe Hemorrhoid Cream acts quicker with ingredients formulated to penetrate deep and take action faster. You can add the creme to wipes, applicators, or just use a finger for external hemorrhoids.
FIRST-AID ESSENTIALS: Globe's Hemorrhoid Cream is a must have for any First-Aid Kit or Medicine Cabinet. This medicated cream is perfect for even the most sensitive cases and gives relief faster. We cut out unnecessary fillers and deliver effective results.

Bestseller No. 7

Mayinglong Musk Hemorrhoids Ointment (3 x 10g Tubes), 30g - Maximum Strength Formula for Hemorrhoidal Fast Relief, Soothes Itching, Burning & Discomfort - Fast-Acting Treatment to Shrink Swelling

INGREDIENTS USED IN ASIA SINCE 1582. An effective ointment for hemorrhoids, Mayinglong Hemorrhoid Ointment is now available in the US, distributed by Trifecta Pharmaceuticals USA.
HOW IT WORKS: Shrinks swollen Hemorrhoid tissue. The zinc carbonate (in calamine) has been shown to reduce the size of blood vessels both for internal and external hemorrhoids
EASY TO USE & VERY COST EFFICIENT - This hemorrhoid ointment is the most affordable Hemorrhoid Treatment and with our hemorrhoids relief system, you'll easily be hemorrhoids free in a few weeks. You will save lots of money by not having to go to the doctor.
REDUCES HEAT AND INFLAMMATION The borates in Borax, compounds in Bovis Calculus and proteins in Margarita all work to reduce heat and swelling, commonly seen in hemorrhoid
RELIEVES HEMORRHOIDS: As heat, swelling and the inflammatory reaction are reduced, the associated pain and discomfort subsides.

Bestseller No. 8

Boiron HemCalm Ointment for Hemorrhoid Relief of Pain, Itching, Swelling or Discomfort - 1 oz

Paraben-free formula targets external hemorrhoids.
Can be used with hemcalm Suppositories for internal hemorrhoids and hemcalm tablets.
Can be applied externally up to four times a day.
Safe to use at the First Sign of Symptoms before discomfort becomes more disruptive.
Recommended for everyone ages 12 and up.

SaleBestseller No. 9

Reejoys Hemorrhoid Cream, Hemorrhoid Treatment, Hemorrhoid & Fissure Ointment, Fast Relief Hemorrhoid Cream Healing Formula, Hemorrhoid Symptom Ointment (0.7 oz)

√ ESSENCE FROM CHINESE MEDICAL PRACTITIONER AND TRADITIONAL MEDICINE- Combined with natural herbs 100% recommended and proven by Chinese medical Practitioner and more effective remedies, our Hemorrhoids cream is thought to be the most powerful formula for hemorrhoid treatment.
√ DOCTOR RECOMMENDED INGREDIENT - Our Hemorrhoids cream is a powerful Hemorrhoids solution trusted by physicians with years of professional experience.
√ SAFE TO USE - Our Hemorrhoids cream is made from natural and gentle ingredients that have been clinically proven to work on relief for Pain, Burning & Itching, Reduces Swelling.
√ COMFORTABLE - Our professional herb formula is designed to effectively relieve your pain naturally without smell thus it will not cause inconvenience to your life.
√ EASY TO USE- For external use only. Apply Reejoys Hemorrhoids cream on your affected area twice a day.

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