10 Best dry eye drops (2025)

10 Best dry eye drops (2025) offer effective relief for those suffering from discomfort and irritation. These top-rated products include options like Systane Ultra, Refresh Optive, and TheraTears, which provide long-lasting hydration and protection. Other notable mentions are Blink Tears, Rohto Dry Aid, and GenTeal, known for their soothing properties. For those seeking preservative-free alternatives, brands like Oasis Tears and EyePromise are excellent choices. Additionally, the innovative formulation of Zatidor and the advanced technology in Optase make them stand out. With these options, finding the right dry eye drops has never been easier for optimal eye comfort.

Bestseller No. 1

Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each

#1 Dr Recommended Brand of Artificial Tears*, packaging may vary
Extended Protection
Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
Reduces both the signs and symptoms of dry eye
Quickly soothe irritated eyes wherever you are

SaleBestseller No. 2

iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle

iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz bottle.
Unique Formulation: Hydrating polymers form a protective matrix, moisturizing Hyaluronic Acid holds up to 1000x its weight in moisture, and Trehalose (synthetic ingredient also found in desert plants).
Free of Irritating Preservatives: Sterile, safe for use with contact lenses
Patented ABAK Bottle: preservative-free, dispenses drop-by-drop, and does not stream. The ergonomic bottle is easy to open, easy to hold and squeeze.
iVIZIA – We See a Better Way: for healthy, comfortable eyes

SaleBestseller No. 3

Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)

IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.

SaleBestseller No. 4

TheraTears Extra Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, 0.5 fl oz Bottle, 2 Count(Pack of 1)

Get up to 12 Hours of Hydrating Comfort; TheraTears EXTRA Dry Eye Therapy Lubricant Eye Drops provide EXTRAordinary relief for dry eyes
Discover TheraTears eye drop; one-of-a-kind silky hydration for dry eyes
Lubricating eye drops for extra dry eyes rehydrate; protect against further irritation and support a natural tear pH level
TheraTears Extra Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
TheraTears corrects the salt imbalance that can cause dry eye symptoms

SaleBestseller No. 5

Visine Dry Eye Relief All Day Comfort Lubricant Eye Drops for Up to 10 Hours of Comfort, Dry Eye Drops with Polyethylene Glycol, 0.5 fl. oz

0.5-fluid ounce bottle of Visine Dry Eye Relief All Day Comfort Lubricant Dry Eye Drops to moisturize and soothe dry eyes and protect against further irritation
Sterile moisturizing eye drops start working in seconds to provide temporary relief of burning, eye irritation, and discomfort due to dryness of the eye
These eye drops start to relieve dry eye in seconds
From Visine, a brand backed by 60 years of expertise, these eye drops feature the lubricant polyethylene glycol 400 and provide up to 10 hours of comfort
Visine All Day Comfort Dry Eye Relief Eye Drops are available in a small, convenient-to-carry bottle for convenient relief anywhere, even on-the-go

SaleBestseller No. 6

Blink Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz

Relief with every Blink: Experience extended dry eye symptom relief with Blink Triple Care Lubricating Eye Drops. This 3-in-1 formula instantly soothes, gives extra long-lasting hydration, and seals in moisture.
Dry Eye Lubricant: Discover what makes Blink Triple Care Lubricating Eye Drops different from other eye drops. Our drops for dry eyes have a dual-action moisture seal to lock in moisture for instant, long-lasting relief.
Long-Lasting Hydration: Blink Triple Care Lubricating Eye Drops are formulated with hyaluronate - also found in your eyes - to boost hydration. Hydrate like your tears for extra long-lasting comfort
Reduce Everyday Discomfort: These dops for dry eyes deliver extended relief for moderate to severe dry eye symptoms
Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated.

SaleBestseller No. 7

TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials

TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
TheraTears corrects the salt imbalance that can cause dry eye symptoms
Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness

SaleBestseller No. 8

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)

Fast acting hydration for sensitive eyes
Preservative free tear evaporation protection
Nano droplets for better coverage

SaleBestseller No. 9

OCuSOFT Retaine MGD Ophthalmic Emulsion - Complete Dry Eye Relief - Soothes Red & Irritated Eyes - 30 Count Preservative-Free Single-Use Containers - 0.01 Fl Oz

Retained mgd is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes
Provides long-lasting relief utilizing nova orb,
Proprietary cationic oil emulsion technology that effectively delivers ingredients through electrostatic attraction between positively charged droplets and the negatively charged ocular surface
Retained MGD is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes.
The hypo tonicity of the emulsion adds moisture by lowering the salt concentration of tears while the lipid component lubricates and protects the surface of the eye.

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