10 Best digestive enzymes for dogs (2025)

10 best digestive enzymes for dogs in 2025 are essential for promoting optimal gut health and enhancing nutrient absorption. These enzymes, including bromelain, papain, and amylase, help break down proteins, fats, and carbohydrates, ensuring your dog gets the most from their food. Other top choices like protease, lipase, and cellulase support digestion and alleviate issues like bloating and gas. Additionally, products containing prebiotics and probiotics can further enhance digestive health. Choosing the right digestive enzyme supplement can lead to a happier, healthier dog, making it a vital consideration for pet owners in 2025.

Bestseller No. 1
NaturVet – Digestive Enzymes for Dogs - Plus Probiotics & Prebiotics | Helps Support Diet Change & A Healthy Digestive Tract | for Dogs & Cats | 8 oz Powder
  • DIGESTIVE ENZYMES FOR DOGS - Provides Probiotics for dogs and cats with essential enzymes to help break down food for optimal utilization of nutrients.
  • OPTIMAL SUPPORT - Great for food transitioning, sensitive stomachs and flatulence. A source of: Alpha-Amylase hydrolyzes starch, Protease hydrolyzes proteins, Cellulase breaks down cellulose, and Lipase hydrolyzes triglycerides.
  • EASY TO ADMINISTER - Powder for Dogs and Cats over the age of 6 weeks, add 1/4 rounded teaspoon to each cup of dry or wet food at every feeding.
  • MADE IN THE USA and VETERINARIAN FORMULATED - All NaturVet products are veterinarian formulated and manufactured in the USA in an FDA audited, cGMP compliant facility.
Bestseller No. 2
Pan-tenex | 10x Digestive Enzymes for Dogs - 8.8 Ounces (250 Grams)
  • Highest Potency Available – 10x Porcine Pancreatic Enzyme Powder Maximum Enzyme Levels To Support Digestion Of Fats, Proteins & Carbohydrates Contains Lipase, Amylase & Protease Digestive Enzymes For Nutrient Absorption Acetone-Free | Dust-Free | Low-Odor Formulation Dosed Per Meal, Not Per Cup Of Food | Use Less & Save More
SaleBestseller No. 3
Probiotics for Dogs and Digestive Enzymes - 170 Dog Probiotics Chews - Dog Probiotic - Anti Diarrhea, Upset Stomach & Gas Relief, Constipation, Canine Prebiotic - Pet Fiber Supplement - Gut Health
  • Promotes Digestive Health: This probiotic for dogs is specifically formulated to maintain a healthy gut in dogs of all sizes. They help combat common issues like diarrhea, constipation, and upset stomachs.
  • Advanced Probiotic & Prebiotic Formula: Each chew is packed with essential dog probiotics and digestive enzymes, along with fiber ensuring your canine companion gets the full spectrum of digestive support
  • Ease Stomach Discomfort: Our pet probiotics for dogs contain ingredients known for providing relief from gas, acid, and loose stool, helping your dog feel comfortable and happy. Dog probiotic, probiotic for dogs
  • Formulated for All Dogs: Created with every dog in mind, our probiotic chews for dogs are perfect for all ages and sizes - from playful puppies to wise seniors - so your loyal companion gets the nutrients they need at any stage of life
  • Veterinarian Developed & USA Made: Trust in the premium quality of our dog digestive support supplement, which are formulated by veterinarians and manufactured in the USA within an FDA-registered facility
Bestseller No. 4
Wholistic Pet Organics: Dog Probiotics and Digestive Enzymes Powder - 2 oz - Dog Digestive Support Supplement Prevents Upset Stomach - Gut Health Digest All Probiotics for Dogs and Cats
  • Powerful Dog Probiotic Formula: Formulated to provide high-quality probiotics for dogs and digestive enzymes to support gut health and digestion.
  • Multi-Purpose for Cats & Dogs: A comprehensive probiotic supplement suitable for both dogs and cats, addressing digestive issues and supporting overall health.
  • Prebiotics for Dogs & Cats: Includes prebiotics to complement probiotics, ensuring a healthy gut and improved digestion for both dogs and cats.
  • Organic Digestive Enzymes: Features natural digestive enzymes with probiotics and prebiotics for dogs, enhancing digestion and reducing food-related issues.
  • For Homemade Dog Food: Works as a perfect dog food supplement for homemade dog food, ensuring complete nutrition with essential enzymes and probiotics.
Bestseller No. 5
Digestive Enzymes with Probiotics for Dogs - 120 Soft Chews - Supports Healthy Digestive Tract, Helps Nutrient Absorption, Food Digestion, and Health Maintenance
  • BENEFITS OF DIGESTIVE ENZYMES: This formula helps your dog digest food, which unlocks vitamins, minerals, and other important nutrients so they can be absorbed and utilized in the body. They can also help with upset stomach and diarrhea.
  • PREVENT NUTRIENT DEFICIENCY: If your pet doesn't digest the nutrients it needs, it can result in incomplete food digestion, allowing partially digested food particles to enter the bloodstream from the large intestine, This can cause health concerns in your pet.
  • DOG PROBIOTICS FOR HEALTHY GUT: Included with the digestive enzymes are 90 Million CFU live probiotic spores which supplement depleted bacteria and are vital in maintain proper health. Gut micro flora is involved in resistance to disease.
  • UNIQUE FORMULA: Included in this digestive supplement for dogs is protease, which hydrolyzes protein; amylase, which hydrolyzes carbohydrates; lipase, which hydrolyzes fats; and cellulase, which breaks down cellulose such as corn and wheat.
  • VET RECOMMENDED: These digestive enzymes for dogs are helpful when switch pet food brands or when weaning puppies to pet food. Dosage varies by pet size. These 120 chewable pills are delicious and enough to last for up to 60 days. MADE IN THE USA.
SaleBestseller No. 6
Bark & Whiskers Digestive Enzymes Kibble Diet, for Dogs & Cats, 4.23 oz. (120 g), 150 Scoops, Promotes Carb & Starch Breakdown, Veterinarian Formulated, Non-GMO, Dr. Mercola
  • Specifically designed for our furry friends on a kibble-based diet, Bark & Whiskers Digestive Enzymes – Kibble Diet provides additional enzymes for properly digesting the carbs and starches often found in high quantities in kibble
  • This formula is also made for pets with sensitive stomachs, as it contains lower levels of pancreatic enzymes than other pet foods, which can boost stomach acid and potentially irritate tummies
  • This blend is made with 9 enzymes, including Porcine Pancreas, Papain from Papaya, Bromelain from Pineapple and Betaine Hydrochloride for optimal digestion of high-carb diets
  • The raw materials this product is made from are tested and retested by our high-quality manufactures to ensure you and your pet receive the best possible product
  • Bark & Whiskers is bridging the gap between you and your pet’s everyday wellness regimens with veterinarian-formulated products for farther walks, longer play and more memories together – because they’re family, too
Bestseller No. 7
Digestive Enzymes for Dogs - Dog Digestive Enzymes - Supports a Healthy Digestive Tract & Much More - Dog Digestive Support - Dog Enzymes - Dog Enzymes Digestive - Dog Digestive Enzyme - 1 fl oz
  • Digestive Harmony: Our Dog Digestive Support Tincture is specially formulated to promote optimal digestion and gastrointestinal health in your furry companion, ensuring they enjoy every meal with ease and comfort.
  • Soothing Relief: Say goodbye to digestive woes! Our tincture's gentle yet effective blend of natural ingredients calms and soothes your dog's digestive system, alleviating symptoms of indigestion, gas, bloating, and diarrhea.
  • Balanced Gut Microbiome: Experience the transformative power of our tincture as it supports a healthy balance of beneficial bacteria in your dog's gut. By promoting gut microbiome health, it aids in digestion and nutrient absorption, ensuring your pet thrives from the inside out.
  • Enhanced Nutrient Absorption: Give your dog the gift of better nutrient absorption with our advanced formula. By aiding digestion, our tincture ensures your pet gets the most out of every meal, leading to improved overall health and vitality.
  • Trusted Quality: Crafted with care and backed by science, our Dog Digestive Support Tincture is made from premium ingredients to deliver optimal results. Give your beloved companion the digestive support they deserve and watch them thrive with every wag of their tail. If you are not fully satisfied with your purchase, then please message us for a refund.
Bestseller No. 9
Digestive Enzymes for Dogs & Cats : Protein, Carbs, Starches & Fats Digestion : Supports Diet Change : Enzyme Miracle (364 Scoops, Powder)
  • ★ COMPLETE DIGESTIVE ENZYME SUPPLEMENT for dogs and cats. Enzyme Miracle has been supporting amazing digestive health in dogs and cats since 2009.
  • ★ TRANSFORMATIVE TO HEALTH : 1 economical scoop is undetectable on your pet's food and delivers 11 types of plant-based enzymes plus bromelain to break down proteins, fats, cellulose, carbs, and starches. Perfect complement to probiotics, omega-3 supplements, kibble, raw diets, and natural dog foods.
  • ★ SUPPORTS DIET CHANGES & COMPLETE DIGESTION : Great for food transitions and sensitive tummies. Recommended for pets with digestive stress, indigestion, pancreatic problems, excessive shedding, gas, irregular stools and unexplained weight loss.
  • ★ PURE : 100% Natural - 100% Safe - Unflavored Powder - Easy Dosing - No Byproducts - No Wheat - No Dairy - No Eggs - No Soy - No Flavorings - No Animal Ingredients. Perfect for dogs and cats eating a processed or cooked diet. Renders cooked diets closer to raw with a super premium blend of enzymes that break down fats, carbohydrates, proteins, fiber, even yeast and fungus! Your pet will feel great and experience reduced shedding, improved allergies, vibrant skin and coat, and natural energy.**
  • ★ RIGOROUSLY TESTED : Third party testing. Manufactured in the USA at a GMP certified facility.
SaleBestseller No. 10
Bark&Spark Dog Probiotics & Digestive Enzymes (Gut Health) Allergy & Itchy Skin - Pet Diarrhea Gas Treatment Upset Stomach Relief, Digestion Health Prebiotic Supplement Tummy Treat (120Ct Chicken)
  • Top-Tier Results: A staggering 8 out of 10 dogs witness great benefits within the first month of daily use. Ideal for puppies to old senior dogs, our advanced dog probiotics and digestive enzymes enhance gut health in small, medium, and large dogs.
  • Buy with Confidence: Enjoy a full refund without returns on our probiotic chews for dogs. Our 90-day guarantee and 24/7 customer service offer peace of mind for pet owners seeking the best canine gut and immune health supplements.
  • Premium Formula: Our probiotics for dogs for allergies and itchy skin are enriched with a five-strain probiotic & prebiotic blend + enzyme & pumpkin fiber to alleviate paws licking, diarrhea, gas, constipation, soft stool & upset stomach issues.
  • Easier Digestion: These dog probiotic chews include enzymes for consistent dog digestive support, promoting healthy gut flora. Ideal for picky eaters with food sensitivities, these chicken-flavor yummy chews help maintain a healthy, active lifestyle.
  • Quality Assured: Bark&Spark pre probiotics for dogs are made in the USA. They're a chewy, tasty treat for dogs of all ages & breed (puppy, adult to older doggy), ensuring daily digestive and immunity strength with every chew.
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