10 best detergents for sensitive skin in 2025 offer gentle yet effective cleaning solutions for those prone to irritation. These specially formulated detergents are free from harsh chemicals, dyes, and fragrances, ensuring a soothing wash for delicate skin. Brands like Seventh Generation, All Free Clear, and Tide Free & Gentle lead the market, providing hypoallergenic options that maintain fabric integrity while minimizing allergic reactions. Additionally, eco-friendly choices like Mrs. Meyer's Clean Day and Ecover cater to environmentally conscious consumers. With these top picks, you can enjoy clean laundry without compromising your skin's health.
SaleBestseller No. 1
Arm & Hammer Sensitive Skin Free & Clear, 140 Loads Liquid Laundry Detergent, 140 Fl oz
- One 140 fl oz bottle of ARM and HAMMER Sensitive Skin Free and Clear Liquid Laundry Detergent, Free and Clear Detergent that cleans 140 medium loads when used as directed
- Dermatologist-tested, hypoallergenic laundry detergent that's gentle on skin but tough on stains and odors, making it an ideal soap for sensitive skin
- Dye-free, worry-free detergent with no perfumes or preservatives is certified 100% by SkinSAFE (1), (1) Certified by SkinSAFE to exclude 100% of their topmost considered skin allergens. In partnership with SkinSAFEproducts.com
- With trusted ARM and HAMMER Baking Soda, this HE detergent is formulated to deeply clean clothes while being gentle on skin
- HE laundry detergent is concentrated with 2X powerful stain fighters in every load versus leading value detergent, making it an effective and efficient laundry detergent
Bestseller No. 2
ARM & HAMMER Sensitive Skin Free Clear, 170 Loads Liquid Laundry Detergent, 170 Fl oz
- One 170 fl oz bottle of ARM & HAMMER Sensitive Skin Free & Clear Liquid Laundry Detergent, Free and Clear Detergent that cleans 170 medium loads when used as directed
- Dermatologist-tested, hypoallergenic laundry detergent that's gentle on skin but tough on stains and odors, making it an ideal soap for sensitive skin
- Dye-free, worry-free detergent with no perfumes or preservatives is certified 100% by SkinSAFE (1), (1) Certified by SkinSAFE to exclude 100% of their topmost considered skin allergens. In partnership with SkinSAFEproducts.com
- With trusted ARM & HAMMER Baking Soda, this HE detergent is formulated to deeply clean clothes while being gentle on skin
- HE laundry detergent is concentrated with 2X powerful stain fighters in every load versus leading value detergent, making it an effective and efficient laundry detergent
SaleBestseller No. 3
Arm & Hammer Sensitive Skin Plus Fresh Scent, 105 Loads Liquid Laundry Detergent, 105 Fl oz
- One 105 fl oz bottle of ARM & HAMMER Sensitive Skin Laundry Detergent, Fresh Scent Liquid Laundry Detergent that cleans 105 medium loads when used as directed
- Dermatologist-tested laundry detergent that's gentle on skin but tough on stains and odors, making it an ideal soap for sensitive skin
- Dye-free detergent with a hypoallergenic fresh scent that has been tested by dermatologists and has passed four different clinical tests, so you can use this detergent worry-free
- With trusted ARM & HAMMER Baking Soda, this HE laundry detergent is formulated to deeply clean clothes while being gentle on skin
- HE laundry detergent is concentrated with 2X powerful stain fighters in every load versus leading value detergent, making it an effective and efficient laundry detergent
Bestseller No. 4
Tide Free & Gentle Laundry Detergent Liquid, HE Compatible, 100 Loads, 132 fl oz, Hypoallergenic Laundry Detergent for Sensitive Skin, Tide Laundry Detergent, Liquid Laundry Detergent
- DEEP CLEAN: Deeper clean that is gentle on skin and removes more residue from dirt, food and stains than the leading Free detergent* *vs. leading national competitor Free detergent
- TRUSTED BY EXPERTS: From Tide, the #1 brand used by dermatologists. Trust the power of our liquid laundry detergent
- HYPOALLERGENIC: Hypoallergenic detergent liquid. Made with no irritating residues, no dyes and no perfumes for a gentle clean
- 3-IN-1 LAUNDRY DETERGENT: Scent free + hypoallergenic + stain remover. Our laundry soap works hard to help remove stains and keep your clothes fresh
- EXCEPTIONAL CLEANING: No matter what type of machine you have or the water temperature you prefer, Tide Free & Gentle ensures exceptional cleaning results every time. Safe to use on all fabric types
Bestseller No. 5
Tide Simply Clean & Sensitive Laundry Detergent, Cool Cotton Scent, 89 Loads, 117 Fl Oz, Tide Laundry Detergent, Laundry Soap
- GENTLE AND ECONOMICAL: Experience the gentle care of Tide Simply laundry detergent, which is not only easy on the skin but also on your wallet
- DESIGNED FOR SENSITIVE SKIN: Our Tide Simply laundry detergent is specifically designed for sensitive skin, with no dyes and only a light fragrance
- POWERFUL CLEANING: 2x the power of baking soda laundry detergent**stain removal of 1 dose vs. 2 doses of the leading detergent with baking soda in a standard, top-loading machine
- EFFECTIVE CLEANING: Tide Simply laundry detergent helps clean fabrics in just 1 wash, making it a reliable washing detergent choice
- COMPATIBLE WITH ALL MACHINES: Our laundry soap is compatible with both HE and standard washing machines, offering versatile use
SaleBestseller No. 6
Tide Simply Liquid Laundry Detergent, Free & Sensitive, 89 Loads, 117 oz, Tide Liquid Laundry Detergent, Laundry Soap
- GENTLE ON SKIN: This Tide Simply laundry detergent is formulated to be gentle on your skin, making it perfect for sensitive individuals
- FREE FROM DYES OR PERFUMES: Tide Simply laundry detergent is free from dyes and perfumes, ensuring a clean and fresh wash without any unnecessary additives
- EFFECTIVE IN COLD WATER: Tide liquid laundry detergent effectively helps clean your clothes even in cold water, saving energy while delivering excellent results
- COMPATIBLE WITH VARIOUS MACHINES: This laundry detergent liquid is compatible with both HE and standard washing machines, making it a versatile washing detergent choice
- EXCELLENT LAUNDRY SOAP: Use this laundry soap for a thorough clean that helps leave your clothes smelling fresh and feeling soft
Bestseller No. 7
Persil Free & Sensitive Liquid Laundry Detergent, Unscented and Hypoallergenic for Sensitive Skin, 2X Concentrated, 82.5 fl oz, 110 Loads
- Persil Free & Sensitive laundry detergent is gentle on skin and tough on stains
- It is hypoallergenic and free of dyes and perfumes
- Persil laundry detergent has fabric protection technology to keep whites and colors vibrant
- Persil laundry detergent protects fabrics, deep cleans, and helps keep clothes looking newer, longer* *vs leading value detergent
- This 2X concentrated formula delivers more cleaning power in every drop vs our standard detergent so you don’t have to use as much to get a gentle deep clean
Bestseller No. 8
Seventh Generation Concentrated Laundry Detergent Liquid Free & Clear Fragrance Free 40 oz
- Seventh Generation Free & Clear Concentrated Laundry Detergent Fragrance-Free has a powerful triple-enzyme formula fights tough stains
- Free & Clear hypoallergenic laundry detergent made for sensitive skin
- A laundry detergent that is EPA Safer Choice Certified and designed with safety in mind
- Concentrated detergent washes 53 medium loads in high-efficiency (HE detergent) or standard machine
- USDA Certified 96 percent Biobased laundry detergent liquid made with plant-based ingredients
Bestseller No. 9
Tide PODS Cold Water Clean, Free and Gentle Laundry Detergent Soap Pacs, Unscented Hypoallergenic Laundry Detergent for Sensitive Skin, 112 Count, Tide PODS Laundry Detergent, Laundry Pacs
- DEEP CLEAN: Experience a deep clean that's gentle on skin with Tide PODS laundry detergent. Tide Free & Gentle PODS laundry detergent are Hypoallergenic, Dermatologist Tested, and Free of dyes and perfumes
- TRUSTED BY EXPERTS: From Tide, the #1 brand used by dermatologists
- HYPOALLERGENIC: Hypoallergenic laundry soap. Made with no irritating residues, no dyes, and no perfumes
- 3-IN-1 CLEAN: A 3-in-1 clean, with concentrated laundry detergent, stain removers, and color protectors
- 100% COMMON STAINS: Each super-concentrated laundry detergent pac of Tide PODS Free & Gentle works on 100% of common stains, even in cold water. Safe to use on all washable fabrics
SaleBestseller No. 10
Tide PODS Free & Gentle Laundry Detergent Soap PODS, 81 Count, Tide PODS Laundry Detergent, Laundry Pacs
- DEEP CLEAN: Experience a deep clean that's gentle on skin with Tide PODS laundry detergent
- TRUSTED BY EXPERTS: From Tide, the #1 brand used by dermatologists
- HYPOALLERGENIC: Hypoallergenic laundry soap. Made with no irritating residues, no dyes, and no perfumes
- 3-IN-1 CLEAN: A 3-in-1 clean, with concentrated laundry detergent, stain removers, and color protectors
- COMMON STAINS: Each super-concentrated laundry detergent pac of Tide PODS Free & Gentle works on common stains, even in cold water