10 best cough suppressants for adults in 2025 offer effective relief for persistent coughs caused by colds or allergies. Leading options include dextromethorphan-based syrups, which work by blocking the cough reflex, and natural remedies like honey and herbal teas that soothe the throat. Popular over-the-counter brands such as Robitussin and NyQuil provide quick relief, while lozenges with menthol can ease irritation. For those seeking non-drowsy options, formulations with guaifenesin help thin mucus. Always consult a healthcare professional before starting any new medication to ensure safety and effectiveness tailored to individual needs.
Bestseller No. 1
Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor - 8 Fl Oz Bottle
- One 8 fluid ounce bottle of Robitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor
- Non drowsy cough medicine that controls and relieves frequent cough, plus thins mucus to relieve chest congestion
- Liquid cough expectorant that's easy to measure and administer
- Raspberry flavored cough and chest congestion expectorant provides fast relief
- Non drowsy cough suppressant relieves symptoms without slowing you down
SaleBestseller No. 2
Robitussin 8 Hour Liqui-gels Cough, Adult Formula - 20 count Liqui-Gels
- One 20 count bottle of Robitussin Adult Long-Acting CoughGels
- Cold medicine helps reduce the urge to cough
- Liquid filled capsules are perfect for at home or on the go
- Long-acting CoughGels control and relieve cough for up to eight hours
- Take two capsules every six to eight hours as needed
Bestseller No. 3
Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant, 14 Tablets
- ACTIVE INGREDIENTS: Amazon Basic Care Maximum Strength Mucus Relief DM tablets contain dextromethorphan HBr and guaifenesin; compare to the active ingredients in Maximum Strength Mucinex DM
- MAXIMUM STRENGTH: 1200 mg of guaifenesin and 60 mg of dextromethorphan HBr team up to take on your toughest cold
- EFFECTIVE: Amazon Basic Care Maximum Strength Mucus-DM clears your chest congestion and eases the intensity of coughing
- COUGH SUPPRESSANT: This 12-hour cough medicine contains dextromethorphan HBr for cough relief; it relieves the impulse to cough to help you get to sleep
- COUGH EXPECTORANT: Contains guaifenesin to help loosen phlegm so you can cough up that bothersome mucus; makes coughs more productive
Bestseller No. 4
Maximum Strength Delsym Cough Suppressant, Fast Release Caplets, Lasts up to 8 Hour Day or Night, 20 Count (Packaging May Vary)
- NEW CAPLET FORMAT: Maximum Strength Delsym Cough Suppressant caplets provide relief without the cough medicine taste.
- FAST RELEASE: Lasts up to 8 hours day or night. Temporarily relieves cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants.
- COUGH SUPPRESSANT: Contains Dextromenthorphan (DEX), it works on the part of the brain responsible for the cough reflex, disrupting the communication between the brain and the nerves which provoke the coughing.
- FSA & HSA Eligible: Save up to 30%. Cover out-of-pocket expenses with pre-tax dollars.
- FOR ADULTS AND CHILDREN 12 YEARS AND OVER
Bestseller No. 5
Robitussin Maximum Strength Elderberry Cough Plus Chest Congestion DM, Cough Suppressant for Adults, Providing Liquid Cough and Chest Congestion Relief - 8 Fl Oz
- One 8 fl oz bottle of Robitussin Maximum Strength Elderberry Cough Plus Chest Congestion DM Cough Medicine for Adults, Cough and Chest Congestion Relief Liquid
- Provides temporary relief from cough symptoms for up to 4 hours
- Mucus relief expectorant helps thin mucus and helps provide congestion relief
- Maximum strength cough medicine for adults made with real elderberries for flavor
- Cough medicine formula provides powerful relief
Bestseller No. 6
Delsym Cough Relief Medicine, Powerful Cough Relief for 12 Good Hours, Cough Suppressing Liquid, 1 Pharmacist Recommended, Orange Flavor Adult 3 Fl Oz (Pack of 1)
- 12 Hour Cough Relief
- Also available in Grape Flavor
- Cough Suppressant for Day or Night Use
- Controls cough with active ingredient dextromethorphan polistirex extended-release suspension cough suppressant
Bestseller No. 7
Amazon Basic Care Tussin Cough Plus Chest Congestion DM Syrup, Raspberry Flavor, 8 fl oz (Pack of 1)
- ACTIVE INGREDIENTS: This product contains dextromethorphan HBr and guaifenesin which compare to the active ingredients in Robitussin Cough Plus Chest Congestion DM
- COUGH SUPPRESSANT: Temporarily relieves cough due to minor throat and bronchial irritation as may occur with a cold
- EXPECTORANT: Helps loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes for mucus and chest congestion relief
- EFFECTIVE RELIEF: Trust Amazon Basic Care Tussin Cough Plus Chest Congestion DM to effectively relieve cough, chest congestion and mucus
- NON-DROWSY: This non-drowsy cough syrup can be taken every four hours to soothe coughs and thin mucus; for ages 12 and older; alcohol and gluten free
Bestseller No. 8
Delsym Adult Cough Suppressant Liquid, Grape Flavor, 5 Ounce
- Controls & Supresses Cough
- Advanced time-release formula that works immediately
- Provides relief for up to 12 hours
- Suitable for Day & Night
- Sulfite & Alcohol Free