10 Best colic drops for newborns (2025)

Colic drops for newborns are essential for soothing fussy babies and providing relief from gas and discomfort. In 2025, the 10 best colic drops include popular options like Simethicone, which helps break down gas bubbles, and natural remedies such as gripe water, known for its herbal ingredients. Other top choices feature products with probiotics to support gut health and those free from artificial additives. Parents appreciate brands like Little Remedies and Colic Calm for their effectiveness and safety. Always consult a pediatrician before introducing any new product to ensure it’s suitable for your newborn’s needs.

SaleBestseller No. 1
MYLICON Infants Gas Relief Drops for Infants and Babies, Dye Free Formula, 1 Fluid Ounce
  • Mylicon, the #1 pediatrician recommended brand, has been providing safe, effective relief of infant gas for generations
  • Mylicon works gently to speed up a baby’s natural process of getting rid of gas, relieving pressure and discomfort
  • Safe for use with all infants - even the newest of newborns - Mylicon can be used at every feeding, up to 12 times a day (use only as directed)
  • Infant's Mylicon drops contain no saccharin, alcohol or artificial flavors and are gluten-free
  • Contains one 1fl. oz. bottle (100 doses) and an easy to use dosing syringe
SaleBestseller No. 2
BioGaia Protectis Baby Probiotic Drops | Baby Essentials for Colic & Gas Relief | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 5mL
  • SOOTHES CRYING, FUSSING, COLIC & GAS: For over 20 years, BioGaia Baby has been soothing babies with colic & fussy tummies.* Trust BioGaia Baby, the most studied probiotic for colic in the world.
  • SAFE FOR NEWBORNS: Simple & safe for babies from the first day of life. Great for breast-fed, bottle-fed, and mixed-fed infants.
  • NATURALLY RELIEVES BABIES' DIGESTIVE DISCOMFORT: Works naturally in the digestive system to relieve colic, gas, spit-ups, and occasional constipation & diarrhea*
  • NATURALLY FOUND IN BREAST MILK: Unlike drugs and gripe water, BioGaia Baby contains probiotics naturally found in breast milk that ease babies’ digestive discomfort and promote a happy tummy.*
  • NO ALLERGENS, DAIRY, SOY, GLUTEN, SUGAR OR ARTIFICIAL COLORS & FLAVORS: We offer scientifically validated, clinically tested products. We only use safe, ethically sourced & sustainable ingredients. BioGaia always guarantees product quality & safety.
SaleBestseller No. 3
Boiron Camilia Tummy for Colic, Painful Gas, Bloating, & Fussiness- Sterile and Non-Drowsy Liquid Doses - 30 Count
  • GENTLE, HOMEOPATHIC BABY GAS & COLIC DROPS: Camilia Tummy by Boiron, with pure non-GMO ingredients like chamomile, provides gentle relief for tummy pain, bloating, fussiness, crying, and excessive or painful gas caused by gas or colic
  • EASY TO GIVE & MESS-FREE: Camilia Tummy’s liquid doses allow you to simply twist, squeeze and go without the need to measure. This medicine is clear, tasteless, and absorbed in the mouth. Plus, the doses are sterile, hygienic, and do not require refrigeration
  • A BETTER WAY TO FEEL BETTER: Camilia Tummy is a homeopathic colic and gas relief medicine for babies 1 month that has no known interactions with other medications or supplements. It’s made with verified non-GMO pure active ingredients and free of dyes, preservatives, artificial sweeteners, and flavors
  • A TRUSTED BRAND: With more than 90 years of expertise, Boiron medicines are manufactured to meet the highest standards of cGMP and HPUS for purity and quality
SaleBestseller No. 4
Mommy's Bliss Baby Probiotic Drops, Daily Gas, Constipation, and Colic Symptom Relief + Immune Support, Newborns & Up, 0.34 Fl Oz (30 Servings)
  • INFANT PROBIOTICS: Mommy's Bliss baby Probiotic Drops Everyday use the world's most researched probiotic strain. Recommended by pediatricians, Baby Probiotic Drops Everyday are a daily liquid probiotic supplement for babies that you can use from birth.
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • BABY PROBIOTICS: A healthy gut means a happy tummy, and probiotics can help keep baby's belly happy by supporting their digestive system as they digest food and absorb vitamins. Mommy's Bliss probiotics are pediatrician recommended.
  • REMEDIES FOR BABY: Our remedies help ease baby's discomfort & bring back smiles*. From gripe water to help calm colic or tummy troubles, to organic baby cough syrup, baby probiotic drops, or baby vitamins, we help you find your parenting bliss*.
  • MOMMY'S BLISS: Stockup with our gentle remedies to help bring comfort for the occasional cough, or colicky tummy trouble *. Probiotic drops and vitamins help support healthy immune systems*, for healthy, happy kids.
SaleBestseller No. 5
Culturelle Baby Digestive Calm & Comfort Probiotic (Age 0-12 Mos) 8.5Ml, Helps Periodic Colic, Gas, Fussiness, Crying & Digestive Upset In Infants & Newborns, Vegan Non-Gmo Gluten-Free, 1 Mos. Supply
  • FROM THE #1 PEDIATRICIAN RECOMMENDED PROBIOTIC BRAND⟐: Build a strong foundation for infants with Culturelle Baby Digestive Calm + Comfort Drops.* Formulated with two of the most clinically studied probiotics in babies*
  • GENTLE INGREDIENTS: Contains Lactobacillus rhamnosus GG and other probiotics proven to help with occasional tummy troubles and help ease occasional infant colic.* Works naturally to reduce fussiness and crying due to occasional digestive upset*
  • SAFE and EASY TO TAKE: Shake before use; dispense 5 drops once a day onto a spoon, into a bottle or directly into baby’s mouth while breastfeeding; replace cap with dropper; use within 60 days once opened, 1 month supply.
  • Designed for babies aged 0-12 months - Culturelle Baby Digestive Calm and Comfort Probiotics Drops promote healthy development and help build a strong foundation of health for your baby.* Safe to use every day.
  • DESIGNED FOR BABIES 0 12 MONTHS: Culturelle Baby Digestive Calm and Comfort Probiotics Drops helps your baby build a strong foundation of health and promotes healthy development All Mommy’s can rejoice, safe to use everyday
SaleBestseller No. 6
BioGaia Protectis Baby Probiotic Drops | Colic & Gas Relief + Vitamin D | Safe for Newborns | Ease Crying, Fussing, Colic, Gas, Spit-ups & Constipation | No Dairy, Soy & Gluten | 50 Day Supply | 10mL
  • SOOTHES CRYING, FUSSING, COLIC & GAS: For over 20 years, BioGaia Baby has been soothing babies with colic & fussy tummies.* Trust BioGaia Baby, the most studied probiotic for colic in the world.*
  • SAFE FOR NEWBORNS: Simple & safe for babies from the first day of life. Great for breast-fed, bottle-fed, and mixed-fed infants.
  • NATURALLY RELIEVES BABIES' DIGESTIVE DISCOMFORT: Works naturally in the digestive system to relieve colic, gas, spit-ups, and occasional constipation & diarrhea.*
  • NATURALLY FOUND IN BREAST MILK: Unlike drugs and gripe water, BioGaia Baby with Vitamin D contains probiotics naturally found in breast milk that ease babies’ digestive discomfort and promote a happy tummy.*
  • NO ALLERGENS, DAIRY, SOY, GLUTEN, SUGAR OR ARTIFICIAL COLORS & FLAVORS: We offer scientifically validated, clinically tested products.* We only use safe, ethically sourced & sustainable ingredients. BioGaia always guarantees product quality & safety.
SaleBestseller No. 7
Mommy's Bliss Gas Relief Drops Bottle, Simethicone Drops for Infants, Relieves Stomach Discomfort, Safe & Gentle, Ginger Flavor, 1 Fl Oz (Pack of 1)
  • Simethicone-based remedy -Mommy's Bliss Gas relief drops are there to provide fast and safe relief for mothers with babies suffering from stomach discomfort, gas, and general fussiness.
  • Recommended by pediatricians nationwide - parents want to make the best choice for their kids to ease discomfort, and moms everywhere trust Mommy's Bliss as a safe and effective solution for their little ones.
  • Healthful ingredients for healthy families - Ginger extract flavor in a convenient travel size with a taste that your children will love.
  • Safe for newborns - no Artificial colors or flavors; Gluten-, dairy-, and soy-free; alcohol and paraben free.
  • Dropper included in every box and no refrigeration required after opening; 100% recyclable packaging; BPA free.
SaleBestseller No. 8
Colic Calm Gripe Water, Colic & Infant Gas Relief Drops, 2 Ounce
  • Pediatrician recommended Gripe Water alternative
  • Great tasting Gripe Water contains no artificial colors or flavors, sugar, simethicone, wheat, gluten, soy, dairy or animal products; Easy to administer with included dispenser
  • CalmCo Relief: We're on a mission to provide families with innovative supplements; When it comes to you or your family’s health, we make the first line of defense simple and effective
  • Colic calm does not contain: sugar, sodium bicarbonate, simethicone, herbal oils and extracts, soy or dairy, wheat or gluten, animal products, artificial flavors or colors
Bestseller No. 9
Frida Baby Windi Gas Passer, Baby Gas Relief and Colic Baby Relief, Baby Constipation Relief, 10 Count
  • INSTANT BABY GAS RELIEF: A hollow tube that safely, naturally and instantly relieves gas and calms colic.
  • INVENTED BY A PEDIATRIC GASTROENTEROLOGIST: The Windi gas passer is long enough to reach past the muscle that traps the gas and stimulate the sphincter, but has a stopper so you can’t go too far.
  • ALL NATURAL COLIC BABY RELIEF: No drops or ingestible needed, making the Windi a great alternative.
  • SAFE + SANITARY GAS RELIEF FOR INFANTS: Our baby gas reliever is BPA + Latex-Free and completely safe for your baby's bottom, so parents can use it confidently.
  • CONVENIENT + TRAVEL FRIENDLY: 10 Single-use gas relief tubes that you can bring on the go
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