10 Best arthritis cream for knees (2025)

10 Best arthritis cream for knees (2025) offer effective relief for those suffering from joint pain and inflammation. These creams are formulated with powerful ingredients like menthol, capsaicin, and glucosamine, providing targeted relief directly to the affected area. Popular options include Biofreeze, Voltaren Gel, and Tiger Balm, each known for their unique formulations and fast-acting properties. Many of these creams are non-greasy and easy to apply, making them convenient for daily use. With a variety of choices available, individuals can find the perfect arthritis cream to help manage their knee discomfort and improve mobility.

Bestseller No. 1

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief - NEW Easy Open Cap - 150 g

One 5.3 oz/150 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
Number 1 Doctor Recommended topical pain relief brand
Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain

Bestseller No. 2

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief, No Prescription Needed - 1.7 oz/50 g Tube

One 1.7 oz/50 g tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief
Number 1 Doctor Recommended topical pain relief brand
Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
Diclofenac Sodium Topical Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain

SaleBestseller No. 3

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief - NEW Easy Open Cap - 100 g x 2

Two 3.5 oz/100 g tubes of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
Number 1 Doctor Recommended topical pain relief brand
Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain rather than just masking it

Bestseller No. 4

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief - NEW Easy Open Cap - 100 g Tube And 20 g Travel Size Tube

One 3.5 oz/100 g tube and one 0.71 oz/20 g travel size tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
Number 1 Doctor Recommended topical pain relief brand
Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
An Alternative to Pills, Voltaren is a nonsteroidal anti-inflammatory gel that combines the benefits of an arthritis cream and gel for arthritis pain management
Voltaren Arthritis Pain Gel Penetrates Deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain rather than just masking it

SaleBestseller No. 5

Boiron Arnicare Arthritis Cream with Devil’s Claw for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz

DUAL ACTION: Scientifically formulated with Arnica Montana and Harpagophytum (Devil’s Claw) for dual action pain relief. Addresses minor arthritis pain at its source and is suitable for use on all joints.
TOPICAL PAIN RELIEF: The non-greasy light, silky texture quickly absorbs into skin is ideal for sudden flare-ups and soreness.
PLANT-BASED ACTIVE INGREDIENT: Arnica Montana and Harpagophytum are natural pain relievers. No camphor, menthol, or other ingredients that cause burning or stinging and is paraben-free.

Bestseller No. 6

Amish Origins Arthritis Pain Relief Cream - 3.5 oz - Maximum Strength Deep Penetrating for Joint, Muscle, Knee, Back, Feet, Hand, Ankle, Aches, 1 Pack

Provides Fast Relief From Pain: Carefully Formulated With Active Ingredients That Target Pains, Amish Origins Deep Penetrating Pain Relief Cream Is Formulated To Provide Long-Lasting Relief From Pains Associated With Arthritis, Aching Joints, Sore Muscles, Restless Legs, Bruises, Sprains, Backache And More.
Quick-Acting Pain Relief Formula: Amish Origin Medicated Pain Relief Cream Has Earned Its Reputation As One Of The Best On The Market, And That’S Because It Delivers On Its Promises. As A Powerful Pain Relief Cream, Amish Origins Pain Relief Cream Absorbs Quickly And Delivers Fast Relief From Pain.
Greaseless Formula: While Other Pain Relief Formula Leave Behind Annoying Greasy Residues After Application, Not Amish Origins. This Is Because Amish Origins Is Carefully Formulated To Deeply Penetrate The Skin Without The Greasy Feel.
Easy To Use: This Pain Relief Cream Is Easy To Use. Simply Apply A Little Amount Topically, Wherever You Feel Pain, And Watch The Magic Unfolds.
Specially Formulated: To Provide Quick, Therapeutic, And Deep Soothing Relief From Pain, Amish Origins Deep Penetrating Pain Relief Cream Is Perfect For Treating Aching Joints, Restless Legs, Bruises, Arthritis, Headache, Muscle Strains, Backache, Sprains And More.

Bestseller No. 7

Penetrex Joint & Muscle Therapy – Soothing Comfort for Back, Neck, Hands, Feet – Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia – Non-Greasy 2oz Cream

Effective for Joints and Muscles: Penetrex is the whole-body therapy cream you’ve been waiting for; trusted by over 2 million sufferers; offers a different kind of comfort
The Penetrex Difference: Our proprietary blend of natural ingredients leverages the power of arnica, vitamin B6 and MSM to penetrate deeply for joint and muscle discomfort at the source
Premium Experience: Penetrex is a non-greasy, non-sticky, non-staining, paraben-free, cruelty-free and vegan soothing cream without the burn, freeze or strong odor of other products
See Why So Many People Trust Penetrex: Penetrex allows you to get back to doing the things you love
Directions: Apply to back, neck, knee, hand, foot, and more; Penetrex can be used on its own or with other therapies such as heating pads, ice packs, massagers and supplements; apply 3-4 times per day for 7-10 days, then apply as needed

SaleBestseller No. 8

JointFlex Pain Relief Cream for Joint & Arthritis, 4 Oz

FAST ACTING & LONG LASTING PAIN RELIEF CREAM: JointFlex Pain Relief Cream penetrates right to the source of pain to provide powerful relief.
FOR KNEE, SHOULDER, NECK PAIN RELIEF & MORE: Available without a prescription, JointFlex provides pain relief for knees, back, shoulders, hips, wrists, hands—anywhere you need joint pain relief or arthritis pain relief.
UNIQUE SKIN DELIVERY SYSTEM: JointFlex is the only pain relief cream that uses exclusive Fusome skin delivery technology, believed to be a key factor behind its results.
CLINICALLY PROVEN ARTHRITIS PAIN RELIEF: When applied daily as directed, JointFlex provides arthritis pain relief that has been clinically proven for long-term-improving pain relief from osteoarthritis.
PLEASANT SCENT: While some arthritis creams have a lingering smell or sticky residue, JointFlex Pain Relief Cream has a pleasant scent, so you can use it anywhere. Plus, there’s no stain and no grease.

Bestseller No. 9

Hempvana Cream, Ultra Strength Lidocaine Relief of Sore Muscles, AS-SEEN-ON-TV, Achy Knees, and More. Odor-Free & Enriched with Hemp Seed Oil, 4-oz jar

HEMP SEED OIL: our Hempvana Lidocaine Pain Relief Cream is enriched with ultra-moisturizing Hemp Seed Oil
ULTRA STRENGTH 4% LIDOCAINE: the ultra-strength lidocaine formula temporarily relieves pain associated with inflammation, swelling, and stiffness from arthritis, muscle strains, simple backache, and more
TARGET THE PAIN: Hempvana Lidocaine Pain Relief Cream targets pain where it hurts, numbing the area, helping reduce pain by desensitizing the nerves that cause pain
UNIQUE FORMULA: Made with 100% pure cold-pressed hemp seed oil, Turmeric, and FDA-listed pain-fighting 4% lidocaine for active pain relief
NON-GREASY: unlike other ointments and creams that leave behind a greasy mess, Hempvana Lidocaine Pain Relief Cream is non-greasy

Bestseller No. 10

Frankincense & Myrrh Arthritis Pain Reliever Therapy Lotion – Topical Arthritis Pain Relief Cream and Hydrating Skin Repair, Body Pain Relief for Sciatica, Knee, Back, Joints, Neck, 3 Ounces - 1 Pack

TARGETS JOINT AND MUSCLE: Powerful relief for painful nerve, joint, and muscle pain in hands, wrists, elbows, knees, feet, ankles, neck, and back, including sciatica.
FAST ACTING RELIEF: Maximum strength cream penetrates skin quickly for fast, targeted relief with NO negative side effects. Satisfaction guaranteed -- see package for contact information.
EASY TO APPLY: The easy to apply arthritis relief lotion with easy to open flip top cap, temporarily relieves minor pain associated with inflammation, overuse, and stiff, sore muscles and joints.
PREMIUM INGREDIENTS. TRUSTED QUALITY: Blended with the highest quality ingredients including lanolin, shea & cocoa butter and 9 calming essential oils. Manufactured at an FDA registered facility in the U.S.
RECOMMENDED BY CLINICIANS TO RELIEVE PAIN: Over 3,000 U.S. physicians, nurse practitioners and clinicians actively recommend Frankincense & Myrrh to their patients as an effective, non-prescription relief option.

Related Posts